[HTML][HTML] Drug resistance in metastatic breast cancer: tumor targeted nanomedicine to the rescue
Breast cancer, specifically metastatic breast, is a leading cause of morbidity and mortality in
women. This is mainly due to relapse and reoccurrence of tumor. The primary reason for …
women. This is mainly due to relapse and reoccurrence of tumor. The primary reason for …
Advancements in cell membrane camouflaged nanoparticles: a bioinspired platform for cancer therapy
The idea of employing natural cell membranes as a coating medium for nanoparticles (NPs)
endows man-made vectors with natural capabilities and benefits. In addition to retaining the …
endows man-made vectors with natural capabilities and benefits. In addition to retaining the …
Biomimetic metal–organic framework nanoparticles for cooperative combination of antiangiogenesis and photodynamic therapy for enhanced efficacy
Photodynamic therapy (PDT) is a promising anticancer treatment and is clinically approved
for different types of tumors. However, current PDT suffers several obstacles, including its …
for different types of tumors. However, current PDT suffers several obstacles, including its …
In Situ Transforming RNA Nanovaccines from Polyethylenimine Functionalized Graphene Oxide Hydrogel for Durable Cancer Immunotherapy
Messenger RNA (mRNA) vaccine is a promising candidate in cancer immunotherapy as it
can encode tumor-associated antigens with an excellent safety profile. Unfortunately, the …
can encode tumor-associated antigens with an excellent safety profile. Unfortunately, the …
A doxorubicin delivery platform using engineered natural membrane vesicle exosomes for targeted tumor therapy
Targeted drug delivery vehicles with low immunogenicity and toxicity are needed for cancer
therapy. Here we show that exosomes, endogenous nano-sized membrane vesicles …
therapy. Here we show that exosomes, endogenous nano-sized membrane vesicles …
Osteoclast-derived microRNA-containing exosomes selectively inhibit osteoblast activity
W Sun, C Zhao, Y Li, L Wang, G Nie, J Peng, A Wang… - Cell discovery, 2016 - nature.com
MicroRNAs have an important role in bone homeostasis. However, the detailed mechanism
of microRNA-mediated intercellular communication between bone cells remains elusive …
of microRNA-mediated intercellular communication between bone cells remains elusive …
Terrylenediimide-based intrinsic theranostic nanomedicines with high photothermal conversion efficiency for photoacoustic imaging-guided cancer therapy
Activatable theranostic nanomedicines involved in photothermal therapy (PTT) have
received constant attention as promising alternatives to traditional therapies in clinic …
received constant attention as promising alternatives to traditional therapies in clinic …
Inducing enhanced immunogenic cell death with nanocarrier-based drug delivery systems for pancreatic cancer therapy
Immunogenic cell death (ICD) occurs when apoptotic tumor cell elicits a specific immune
response, which may trigger an anti-tumor effect, via the release of immunostimulatory …
response, which may trigger an anti-tumor effect, via the release of immunostimulatory …
Co-delivery of HIF1α siRNA and gemcitabine via biocompatible lipid-polymer hybrid nanoparticles for effective treatment of pancreatic cancer
Hypoxia-inducible factor 1α (HIF1α) has emerged as a promising new target for pancreatic
cancer treatment over the past decade. High expression of HIF-1α increases the drug …
cancer treatment over the past decade. High expression of HIF-1α increases the drug …
[HTML][HTML] Inhalable nanoparticulate powders for respiratory delivery
P Muralidharan, M Malapit, E Mallory… - … , Biology and Medicine, 2015 - Elsevier
Nanoparticles are extensively studied for drug delivery and are proving to be effective in
drug delivery and the diagnostic field. Drug delivery to lungs has its advantages over other …
drug delivery and the diagnostic field. Drug delivery to lungs has its advantages over other …