Biology of Acinetobacter baumannii: Pathogenesis, Antibiotic Resistance Mechanisms, and Prospective Treatment Options
Acinetobacter baumannii is undoubtedly one of the most successful pathogens responsible
for hospital-acquired nosocomial infections in the modern healthcare system. Due to the …
for hospital-acquired nosocomial infections in the modern healthcare system. Due to the …
In pursuit of next-generation therapeutics: Antimicrobial peptides against superbugs, their sources, mechanism of action, nanotechnology-based delivery, and clinical …
A Thakur, A Sharma, HK Alajangi, PK Jaiswal… - International Journal of …, 2022 - Elsevier
Antimicrobial peptides (AMPs) attracted attention as potential source of novel antimicrobials.
Multi-drug resistant (MDR) infections have emerged as a global threat to public health in …
Multi-drug resistant (MDR) infections have emerged as a global threat to public health in …
Machine learning prediction of antimicrobial peptides
Antibiotic resistance constitutes a global threat and could lead to a future pandemic. One
strategy is to develop a new generation of antimicrobials. Naturally occurring antimicrobial …
strategy is to develop a new generation of antimicrobials. Naturally occurring antimicrobial …
Natural compounds and extracts as novel antimicrobial agents
P Guglielmi, V Pontecorvi, G Rotondi - Expert Opinion on …, 2020 - Taylor & Francis
Introduction: Antimicrobial resistance is a worldwide problem accounting for the reduction or
in some cases absence of drugs effectiveness normally used in infections treatment. In the …
in some cases absence of drugs effectiveness normally used in infections treatment. In the …
Komodo dragon-inspired synthetic peptide DRGN-1 promotes wound-healing of a mixed-biofilm infected wound
Cationic antimicrobial peptides are multifunctional molecules that have a high potential as
therapeutic agents. We have identified a histone H1-derived peptide from the Komodo …
therapeutic agents. We have identified a histone H1-derived peptide from the Komodo …
CRISPR/Cas9-mediated knock-in of alligator cathelicidin gene in a non-coding region of channel catfish genome
CRISPR/Cas9-based gene knockout in animal cells, particularly in teleosts, has proven to
be very efficient with regards to mutation rates, but the precise insertion of exogenous DNA …
be very efficient with regards to mutation rates, but the precise insertion of exogenous DNA …
Ab initio Designed Antimicrobial Peptides Against Gram-Negative Bacteria
SS Bobde, FM Alsaab, G Wang… - Frontiers in …, 2021 - frontiersin.org
Antimicrobial peptides (AMPs) are ubiquitous amongst living organisms and are part of the
innate immune system with the ability to kill pathogens directly or indirectly by modulating …
innate immune system with the ability to kill pathogens directly or indirectly by modulating …
Green hydrogel synthesis: emphasis on proteomics and polymer particle-protein interaction
The field of drug discovery has seen significant progress in recent years. These advances
drive the development of new technologies for testing compound's effectiveness, as well as …
drive the development of new technologies for testing compound's effectiveness, as well as …
Computationally Designed AMPs with Antibacterial and Antibiofilm Activity against MDR Acinetobacter baumannii
The discovery of new antimicrobials is necessary to combat multidrug-resistant (MDR)
bacteria, especially those that infect wounds and form prodigious biofilms, such as …
bacteria, especially those that infect wounds and form prodigious biofilms, such as …
Designing anti-microbial peptides against major β-lactamase enzymes in clinically important gram-negative bacterial pathogens: an in-silico study
Anti-microbial resistance (AMR) creating healthcare concerns worldwide requires ardent
exploration of therapeutic alternatives. Although anti-microbial peptides (AMP) are popular …
exploration of therapeutic alternatives. Although anti-microbial peptides (AMP) are popular …