Extraction, isolation and purification of tetrahydrocannabinol from the Cannabis sativa L. plant using supercritical fluid extraction and solid phase extraction

AC Gallo-Molina, HI Castro-Vargas… - The Journal of …, 2019 - Elsevier
The tetrahydrocannabinol (THC) was obtained from Cannabis sativa L. plant material using
supercritical fluid extraction (SFE) and solid phase extraction (SPE). SFE was utilized at …

An emerging micro-scale immuno-analytical diagnostic tool to see the unseen. Holding promise for precision medicine and P4 medicine

NA Guzman, DE Guzman - Journal of Chromatography B, 2016 - Elsevier
Over the years, analytical chemistry and immunology have contributed significantly to the
field of clinical diagnosis by introducing quantitative techniques that can detect crucial and …

[HTML][HTML] Evidence for potential functionality of nuclearly-encoded humanin isoforms

M Bodzioch, K Lapicka-Bodzioch, B Zapala, W Kamysz… - Genomics, 2009 - Elsevier
Humanin (HN) is a recently identified neuroprotective and antiapoptotic peptide derived from
a portion of the mitochondrial MT-RNR2 gene. We provide bioinformatic and expression …

Antibacterial Activity of Synthetic Peptides Derived from Lactoferricin against Escherichia coli ATCC 25922 and Enterococcus faecalis ATCC 29212

MA León-Calvijo, AL Leal-Castro… - BioMed Research …, 2015 - Wiley Online Library
Peptides derived from human and bovine lactoferricin were designed, synthesized, purified,
and characterized using RP‐HPLC and MALDI‐TOF‐MS. Specific changes in the …

Synthetic peptide purification via solid-phase extraction with gradient elution: A simple, economical, fast, and efficient methodology

DS Insuasty Cepeda, HM Pineda Castañeda… - Molecules, 2019 - mdpi.com
A methodology was implemented for purifying peptides in one chromatographic run via solid-
phase extraction (SPE), reverse phase mode (RP), and gradient elution, obtaining high …

Influence of lipidation pattern of the KR12 fragment of peptide LL-37 on its antibacterial and hemolytic activities

E Kamysz, E Sikorska, M Bauer, K Sikora… - International Journal of …, 2023 - mdpi.com
Contemporary medicine has been confronted by multidrug resistance. Therefore, new
antibiotics are sought to alleviate the problem. In this study, we estimated the effect of the …

The evolution of peptide synthesis: From early days to small molecular machines

A Mollica, F Pinnen, S Azzurra… - Current Bioactive …, 2013 - ingentaconnect.com
Peptides and proteins have been known for more than a century, but was only when du
Vigneaud published the first synthesis of oxytocin, that the research on bioactive peptides …

[PDF][PDF] Structure-activity relationship study of synthetic variants derived from the highly potent human antimicrobial peptide hLF (1-11)

C Brouwer, L Roscini, G Cardinali, L Corte… - Cohesive J. Microbiol …, 2018 - researchgate.net
Antimicrobial peptides are omnipresent in nature and act as the first line of defence of the
host against infectious agents. A synthetic antimicrobial peptide derived from the N-terminus …

The coordination abilities of the multiHis-cyclopeptide with two metal-binding centers–potentiometric and spectroscopic investigation

A Kotynia, S Bielińska, W Kamysz, J Brasuń - Dalton Transactions, 2012 - pubs.rsc.org
In this paper we present the formation of mono-and binuclear complexes by the octapeptide
(c (HKHPHKHP)) with copper (II) ions. The ligand was synthesized manually by the solid …

In vitro activity of the histatin derivative P-113 against multidrug-resistant pathogens responsible for pneumonia in immunocompromised patients

A Giacometti, O Cirioni, W Kamysz… - Antimicrobial agents …, 2005 - Am Soc Microbiol
The in vitro activity of the histatin derivative P-113, alone or combined with eight antibiotics,
was investigated against multidrug-resistant strains isolated from clinical specimens of …