Opportunities and challenges of alpha-synuclein as a potential biomarker for Parkinson's disease and other synucleinopathies

P Magalhães, HA Lashuel - npj Parkinson's Disease, 2022 - nature.com
Abstract Parkinson's disease (PD), the second most common progressive
neurodegenerative disease, develops and progresses for 10–15 years before the clinical …

Metasurface‐Enhanced Infrared Spectroscopy: An Abundance of Materials and Functionalities

A John‐Herpin, A Tittl, L Kühner, F Richter… - Advanced …, 2023 - Wiley Online Library
Infrared spectroscopy provides unique information on the composition and dynamics of
biochemical systems by resolving the characteristic absorption fingerprints of their …

Multi-functional metasurface: ultra-wideband/multi-band absorption switching by adjusting guided-mode resonance and local surface plasmon resonance effects

W Li, S Cheng, H Zhang, Z Yi, B Tang… - Communications in …, 2024 - iopscience.iop.org
This study introduces an innovative dual-tunable absorption film with the capability to switch
between ultra-wideband and narrowband absorption. By manipulating the temperature, the …

Wavelength-multiplexed hook nanoantennas for machine learning enabled mid-infrared spectroscopy

Z Ren, Z Zhang, J Wei, B Dong, C Lee - Nature Communications, 2022 - nature.com
Infrared (IR) plasmonic nanoantennas (PNAs) are powerful tools to identify molecules by the
IR fingerprint absorption from plasmon-molecules interaction. However, the sensitivity and …

Artificial intelligence–coupled plasmonic infrared sensor for detection of structural protein biomarkers in neurodegenerative diseases

D Kavungal, P Magalhães, ST Kumar, R Kolla… - Science …, 2023 - science.org
Diagnosis of neurodegenerative disorders (NDDs) including Parkinson's disease and
Alzheimer's disease is challenging owing to the lack of tools to detect preclinical biomarkers …

Surface plasmons-phonons for mid-infrared hyperspectral imaging

H Zhou, D Li, Z Ren, C Xu, LF Wang, C Lee - Science Advances, 2024 - science.org
Surface plasmons have proven their ability to boost the sensitivity of mid-infrared
hyperspectral imaging by enhancing light-matter interactions. Surface phonons, a …

[HTML][HTML] Collective lattice resonances: Plasmonics and beyond

AD Utyushev, VI Zakomirnyi, IL Rasskazov - Reviews in Physics, 2021 - Elsevier
Engineering nanostructures with exceptionally high-Q resonances mediated by the Fano-
type hybridization between discrete states associated with the periodicity of the structure and …

Leveraging of MEMS technologies for optical metamaterials applications

Z Ren, Y Chang, Y Ma, K Shih… - Advanced Optical …, 2020 - Wiley Online Library
Tunable metamaterial devices have experienced explosive growth in the past decades,
driving the traditional electromagnetic (EM) devices to evolve into diversified functionalities …

Quantitative approach to study secondary structure of proteins by FT-IR spectroscopy, using a model wheat gluten system

M Fevzioglu, OK Ozturk, BR Hamaker… - International Journal of …, 2020 - Elsevier
Abstract Amide I and Amide III vibrational modes are frequently used to study protein
secondary structure with Fourier transform infrared (FT-IR) spectroscopy. However, for …

Midinfrared spectroscopic analysis of aqueous mixtures using artificial-intelligence-enhanced metamaterial waveguide sensing platform

J Zhou, Z Zhang, B Dong, Z Ren, W Liu, C Lee - ACS nano, 2022 - ACS Publications
As miniaturized solutions, mid-infrared (MIR) waveguide sensors are promising for label-free
compositional detection of mixtures leveraging plentiful absorption fingerprints. However …