RNA-based therapeutics have shown tremendous promise in disease intervention at the
genetic level, and some have been approved for clinical use, including the recent COVID-19 …

Biomaterials have played an increasingly prominent role in the success of biomedical
devices and in the development of tissue engineering, which seeks to unlock the …

Bone is a hard yet dynamic tissue with remarkable healing capacities. Research to date has
greatly advanced the understanding of how bone heals and has led to marked success in …

The development of responsive biomaterials capable of demonstrating modulated function
in response to dynamic physiological and mechanical changes in vivo remains an important …

Bone fracture followed by delayed or non-union typically requires bone graft intervention.
Autologous bone grafts remain the clinical “gold standard”. Recently, synthetic bone grafts …

Thiolated polymers designated “thiomers” are obtained by covalent attachment of thiol
functionalities on the polymeric backbone of polymers. In 1998 these polymers were first …

Globally, more than 1.5 million patients undergo bone graft surgeries annually, and the
development of biomaterial scaffolds that mimic natural bone for bone grafting remains a …

Bone defects caused by injury, disease, or congenital deformity remain a major health
concern, and efficiently regenerating bone is a prominent clinical demand worldwide …

The need of tissue and organ for transplantation to repair or replace damaged tissues is
significantly higher than the availability of donated organs. Tissue engineering that develops …

Summary TYRO3, AXL, and MERTK constitute the TAM family of receptor tyrosine kinases,
activated by their ligands GAS6 and PROS1. TAMs are necessary for adult homeostasis in …