Exosomal ncRNAs in liquid biopsies for lung cancer

MS Hussain, G Gupta, N Ghaboura, E Moglad… - Clinica chimica acta, 2024 - Elsevier
Exosomal non-coding RNAs (ncRNAs) have become essential contributors to advancing
and treating lung cancers (LCs). The development of liquid biopsies that utilize exosomal …

Connecting the dots: LncRNAs in the KRAS pathway and cancer

M Maqbool, MS Hussain, AS Bisht, A Kumari… - … -Research and Practice, 2024 - Elsevier
Long non-coding RNAs (lncRNAs) have been identified as important participants in several
biological functions, particularly their complex interactions with the KRAS pathway, which …

Nurturing hope: uncovering the potential of herbal remedies against amyotrophic lateral sclerosis

M Gupta, MS Hussain, R Thapa, AA Bhat, N Kumar - PharmaNutrition, 2024 - Elsevier
Background Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease, as
currently available medications such as riluzole and edaravone aim to slow disease …

Multi-omics analysis reveals the genetic aging landscape of Parkinson's disease

Z Wang, Z Zhang, P Li, Q Cao, P Fan, H **a, X Yang - Scientific Reports, 2024 - nature.com
Parkinson's disease (PD) is the second most common age-related neurodegenerative
disease after Alzheimer's disease. Despite numerous studies, specific age-related factors …

Non-coding RNAs in BRAF-mutant melanoma: targets, indicators, and therapeutic potential

S Afsar, RU Syed, WMA Khojali, N Masood… - Naunyn-Schmiedeberg's …, 2024 - Springer
Melanoma, a highly aggressive skin cancer, is often driven by BRAF mutations, such as the
V600E mutation, which promotes cancer growth through the MAPK pathway and contributes …

[HTML][HTML] Methamphetamine Increases Tubulo-Vesicular Areas While Dissipating Proteins from Vesicles Involved in Cell Clearance

G Lazzeri, P Lenzi, CL Busceti… - International Journal of …, 2024 - mdpi.com
Cytopathology induced by methamphetamine (METH) is reminiscent of degenerative
disorders such as Parkinson's disease, and it is characterized by membrane organelles …

Role of long non-coding RNAs in neurofibromatosis and Schwannomatosis: pathogenesis and therapeutic potential

MS Hussain, S Sharma, A Kumari, A Kamran… - …, 2024 - Taylor & Francis
Neurofibromatosis (NF) is identified as genetic disorder characterized by multiple tumors on
nerve tissues. NF1 is the most prevalent form, identified by neurofibromas and skin changes …

Exploring ncRNAs in epilepsy: From oxidative stress regulation to therapy

K Pant, A Sharma, SV Menon, H Ali, WH Almalki… - Brain Research, 2024 - Elsevier
Epilepsy is a prevalent neurological illness which is linked with high worldwide burdens.
Oxidative stress (OS) is recognized to be among the contributors that trigger the …

MicroRNAs in Parkinson's disease: From pathogenesis to diagnostics and therapeutic strategies

D Zheng, J Chween - Neuroscience, 2025 - Elsevier
Parkinson's disease (PD) is a prevalent neurodegenerative disorder characterized by
pathological changes, including the loss of dopaminergic neurons and abnormal …

Therapeutic Approaches to Microglial Dysfunction in Alzheimer's Disease: Enhancing Phagocytosis and Metabolic Regulation

WH Almalki, SS Almujri - Pathology-Research and Practice, 2024 - Elsevier
Microglia are essential in neurogenesis, synaptic pruning, and homeostasis. Nevertheless,
aging, and cellular senescence may modify their role, causing them to shift from being …