Engineering hydrogels as extracellular matrix mimics
Extracellular matrix (ECM) is a complex cellular environment consisting of proteins,
proteoglycans, and other soluble molecules. ECM provides structural support to mammalian …
proteoglycans, and other soluble molecules. ECM provides structural support to mammalian …
Islets transplanted in immunoisolation devices: a review of the progress and the challenges that remain
The concept of using an immunoisolation device to facilitate the transplantation of islets
without the need for immunosuppression has been around for more than 50 yr. Significant …
without the need for immunosuppression has been around for more than 50 yr. Significant …
Structured biopolymer-based delivery systems for encapsulation, protection, and release of lipophilic compounds
A Matalanis, OG Jones, DJ McClements - Food hydrocolloids, 2011 - Elsevier
Food-grade biopolymers, such as proteins and polysaccharides, can be used to create a
diverse range of delivery systems suitable for encapsulating, protecting, and delivering …
diverse range of delivery systems suitable for encapsulating, protecting, and delivering …
Multizone paper platform for 3D cell cultures
In vitro 3D culture is an important model for tissues in vivo. Cells in different locations of 3D
tissues are physiologically different, because they are exposed to different concentrations of …
tissues are physiologically different, because they are exposed to different concentrations of …
Magnetic‐Based Strategies for Regenerative Medicine and Tissue Engineering
The fabrication of biological substitutes to repair, replace, or enhance tissue‐and organ‐
level functions is a long‐sought goal of tissue engineering (TE). However, the clinical …
level functions is a long‐sought goal of tissue engineering (TE). However, the clinical …
Materials for diabetes therapeutics
KM Bratlie, RL York, MA Invernale… - Advanced …, 2012 - Wiley Online Library
This review is focused on the materials and methods used to fabricate closed‐loop systems
for type 1 diabetes therapy. Herein, we give a brief overview of current methods used for …
for type 1 diabetes therapy. Herein, we give a brief overview of current methods used for …
Enhanced function of immuno-isolated islets in diabetes therapy by co-encapsulation with an anti-inflammatory drug
TT Dang, AV Thai, J Cohen, JE Slosberg… - Biomaterials, 2013 - Elsevier
Immuno-isolation of islets has the potential to enable the replacement of pancreatic function
in diabetic patients. However, host response to the encapsulated islets frequently leads to …
in diabetic patients. However, host response to the encapsulated islets frequently leads to …
[HTML][HTML] Membranes to achieve immunoprotection of transplanted islets
J Schweicher, C Nyitray, TA Desai - Frontiers in bioscience …, 2014 - ncbi.nlm.nih.gov
Transplantation of islet or beta cells is seen as the cure for type 1 diabetes since it allows
physiological regulation of blood glucose levels without requiring any compliance from the …
physiological regulation of blood glucose levels without requiring any compliance from the …
Elaborate design strategies toward novel microcarriers for controlled encapsulation and release
Microencapsulation and the controlled release of bioactive agents have long been
investigated and exploited to both improve the fundamental understanding of cell …
investigated and exploited to both improve the fundamental understanding of cell …
A three-dimensional neuronal culture technique that controls the direction of neurite elongation and the position of soma to mimic the layered structure of the brain
A Odawara, M Gotoh, I Suzuki - RSC advances, 2013 - pubs.rsc.org
Reconstruction techniques can mimic tissue structure using three-dimensional (3D)
substrates or scaffolds to facilitate functional tissue engineering for transplantation or robust …
substrates or scaffolds to facilitate functional tissue engineering for transplantation or robust …