Immune-related adverse events and anti-tumor efficacy of immune checkpoint inhibitors

S Das, DB Johnson - Journal for immunotherapy of cancer, 2019 - Springer
Although immune checkpoint inhibitors (ICIs) have transformed the treatment landscape for
patients with many advanced malignancies, only 15–60% of patients respond, leaving a …

[HTML][HTML] Effectiveness and safety of immunotherapy in NSCLC patients with ECOG PS score≥ 2–systematic review and meta-analysis

B Tomasik, M Bieńkowski, M Braun, S Popat… - Lung Cancer, 2021 - Elsevier
Abstract Background Immune checkpoint inhibitors (ICIs) are standard of care in advanced
non-small cell lung cancer (NSCLC), however their status in patients with poor performance …

Performance status and end‐of‐life care among adults with non–small cell lung cancer receiving immune checkpoint inhibitors

LA Petrillo, A El‐Jawahri, RD Nipp, MRL Lichtenstein… - Cancer, 2020 - Wiley Online Library
Background Adults with impaired performance status (PS) often receive immune checkpoint
inhibitors (ICIs) for advanced non–small cell lung cancer (NSCLC) despite limited efficacy …

Risk factors for immune‐related adverse events from anti‐PD‐1 or anti‐PD‐L1 treatment in an Asian cohort of nonsmall cell lung cancer patients

Y Huang, YY Soon, F Aminkeng, SH Tay… - … Journal of Cancer, 2022 - Wiley Online Library
Immune‐related adverse events (IrAEs) of immune checkpoint inhibitors (ICIs) can be
serious and unpredictable. We examine the incidence rate and risk factors for IrAEs in an …

[HTML][HTML] Efficacy and immune-related adverse event associations in avelumab-treated patients

K Kelly, J Manitz, MR Patel, SP D'Angelo… - … for Immunotherapy of …, 2020 - ncbi.nlm.nih.gov
Background Adverse events (AEs) of special interest that arise during treatment with
immune checkpoint inhibitors, including immune-related AEs (irAEs), have been reported to …

Association of immune-related adverse events and efficacy in advanced non-small-cell lung cancer: a systematic review and meta-analysis

Y Zhou, H Chen, L Tang, Y Feng, Y Tao, L Huang… - …, 2023 - Taylor & Francis
Aim: This study aimed to explore the association of immune-related adverse events (irAEs)
with efficacy in advanced non-small-cell lung cancer (NSCLC). Materials & methods: A …

[PDF][PDF] Immune-related adverse events and outcomes in patients with advanced non–small cell lung cancer: a predictive marker of efficacy?

J Remon, N Reguart, E Auclin, B Besse - Journal of Thoracic Oncology, 2019 - Elsevier
Dr. Reguart reports personal fees from MSD, personal fees from Bristol-Myers, personal fees
from Roche, personal fees from Boehringer Ingelheim, personal fees from Guardant Health …

Nivolumab plus ipilimumab combination therapy for the first-line treatment NSCLC: evidence to date

J Remon, L Esteller, Á Taus - Cancer Management and Research, 2019 - Taylor & Francis
Immune checkpoint inhibitors (ICI) as monotherapy in selected patients as well as in
combination with chemotherapy have become the standard of care in the first-line treatment …

Les avancées dans la prise en charge des cancers bronchopulmonaires: ce qui change pour le réanimateur

J Pinsolle, N Terzi, L Ferrer, MG Levra… - Médecine Intensive …, 2019 - revue-mir.srlf.org
Résumé Le cancer bronchopulmonaire (CBP) est la première cause de mortalité par cancer
en France et dans le monde, mais son pronostic tend à s' améliorer depuis une dizaine …

[CITATION][C] Nivolumab plus ipilimumab combination therapy for the first-line treatment NSCLC: evidence to date

Á Taus García, J Remon, L Esteller - 2019 - Dove Medical Press