The microbiomes on human body surfaces affect health in multiple ways. They include not
only commensal or mutualistic bacteria but also potentially pathogenic bacteria, which can …

Ribosomally synthesized and post-translationally modified peptides (RiPPs) are a natural
product class that has undergone significant expansion due to the rapid growth in genome …

Escherichia coli is the most researched microbial organism in the world. Its varied impact on
human health, consisting of commensalism, gastrointestinal disease, or extraintestinal …

Cancer is one of the momentous causes of death worldwide despite the availability of
advance detection and treatment methods. The present chemotherapeutic treatments are …

Despite highly specialized international interventions and policies in place today, the rapid
emergence and dissemination of resistant bacterial species continue to occur globally …

Engineered microbes are rapidly being developed for the delivery of therapeutic modalities
to sites of disease. Escherichia coli Nissle 1917 (EcN), a genetically tractable probiotic with …

Antibiotic resistance is currently one of the most important public health problems. The
golden age of antibiotic discovery ended decades ago, and new approaches are urgently …

Evolution is the hallmark of life. Descriptions of the evolution of microorganisms have
provided a wealth of information, but knowledge regarding “what happened” has precluded …

Biofilms are communities of microorganisms that are attached to a biological or abiotic
surface and are surrounded by a self-produced extracellular matrix. Cells within a biofilm …

Animal hosts have initiated myriad symbiotic associations with microorganisms and often
have maintained these symbioses for millions of years, spanning drastic changes in …