Serotonin is a phylogenetically ancient biogenic amine that has played an integral role in
maintaining energy homeostasis for billions of years. In mammals, serotonin produced …

The microbial community of the gut conveys significant benefits to host physiology. A clear
relationship has now been established between gut bacteria and host metabolism in which …

Abstract Serotonin (5-HT) has traditional roles as a key neurotransmitter in the central
nervous system and as a regulatory hormone controlling a broad range of physiological …

Modulatory effects of serotonin (5‐Hydroxytryptamine [5‐HT]) have been seen in hepatic,
neurological/psychiatric, and gastrointestinal (GI) disorders. Probiotics are live …

Type 2 diabetes (T2D) is potentially linked to disordered tryptophan metabolism that
attributes to the intricate interplay among diet, gut microbiota, and host physiology. However …

Obesity has reached epidemic proportion worldwide and in all ages. Available evidence
points to a multifactorial pathogenesis involving gene predisposition and environmental …

The worldwide epidemics of obesity and diabetes have been linked to increased sugar
consumption in humans. Here, we review fructose and glucose metabolism, as well as …

Nonalcoholic fatty liver disease (NAFLD) is increasing in worldwide prevalence, closely
tracking the obesity epidemic, but specific pharmaceutical treatments for NAFLD are lacking …

Obesity has reached epidemic proportions globally. Although modern adoption of a
sedentary lifestyle coupled with energy-dense nutrition is considered to be the main cause …

The gut microbiome is an established regulator of aspects of host metabolism, such as
glucose handling. Despite the known impacts of the gut microbiota on host glucose …