Numerous key biological processes rely on the concept of multivalency, where ligands
achieve stable binding only upon engaging multiple receptors. These processes, like viral …

Gaining insights into the intercellular receptor-ligand binding is of great importance for
understanding numerous physiological and pathological processes, and stimulating new …

Biomolecular condensates (BCs) are fluid droplets that form in biological cells by liquid–
liquid phase separation. Their major components are intrinsically disordered proteins. Vast …

Cell membranes, mediator of many biological mechanisms from adhesion and metabolism
up to mutation and infection, are highly dynamic and heterogeneous environments …

The specific binding of the ubiquitous 'marker of self'protein CD47 to the SIRP α protein
anchored in the macrophage plasma membrane results in the inhibition of the engulfment of …

Gaining insight into the in situ receptor–ligand binding is pivotal for revealing the molecular
mechanisms underlying the physiological and pathological processes and will contribute to …

The addition of both cell-targeting moieties and polyethylene glycol (PEG) to nanoparticle
(NP) drug delivery systems is a standard approach to improve the biodistribution, specificity …

Nanoparticles (NPs) have been widely applied as drug carriers in drug delivery, due to their
unique physical and structural properties. To achieve the drug delivery purpose, receptor …

Cell adhesion involved in biological processes such as cell migration, immune responses,
and cancer metastasis, is mediated by the specific binding of receptor and ligand proteins …

Cell adhesion on a supported lipid bilayer (SLB) functionalized with ligand proteins is a
widely-used cell-mimetic model for the study of the trans receptor-ligand interaction that …