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Recent developments in synthetic α-glucosidase inhibitors: A comprehensive review with structural and molecular insight
Diabetes mellitus is the prominent metabolic disorder affecting 422 million people around
the globe and cause severe associated problems like kidney disorders, heart and nervous …
the globe and cause severe associated problems like kidney disorders, heart and nervous …
Recent insights about pyrrolidine core skeletons in pharmacology
S Poyraz, HA Döndaş, NY Döndaş… - Frontiers in …, 2023 - frontiersin.org
To overcome numerous health disorders, heterocyclic structures of synthetic or natural origin
are utilized, and notably, the emergence of various side effects of existing drugs used for …
are utilized, and notably, the emergence of various side effects of existing drugs used for …
Sonochemical synthesis of New Thiazolidin-4-one derivatives as potent anticancer and antimicrobial agents with Docking design, and Energy gap estimation
Thiazolidin-4-ones have important biological features, which has led to the development of
new derivatives employing an efficient ultrasonic method. Schiff base derivatives were …
new derivatives employing an efficient ultrasonic method. Schiff base derivatives were …
[HTML][HTML] Design, synthesis and bioevaluation of new vanillin hybrid as multitarget inhibitor of α-glucosidase, α-amylase, PTP-1B and DPP4 for the treatment of type-II …
Diabetes mellitus (DM) is a real challenge to the recent era and is one of the major diseases
for initiating life-threatening disorders. In current research, a compound was designed by …
for initiating life-threatening disorders. In current research, a compound was designed by …
Interfacial phenomena and surface protection of N80-carbon steel in acidic environments using thiazolidinediones: an experimental and computational analysis
In petrochemical engineering, a pressing challenge is the corrosion of N80 carbon steel
(N80-CS) in strong acidic conditions like 15 wt% HCl, impacting both mechanical integrity …
(N80-CS) in strong acidic conditions like 15 wt% HCl, impacting both mechanical integrity …
Recent advances of α-glucosidase inhibitors: a comprehensive review
Background: Diabetes mellitus (DM) is a critical health issue prevailing in nearly half a
billion people worldwide. It is one of the most threatening metabolic diseases. Type 2 DM is …
billion people worldwide. It is one of the most threatening metabolic diseases. Type 2 DM is …
SAR and lead optimization of (Z)-5-(4-hydroxy-3-methoxybenzylidene)-3-(2-morpholinoacetyl) thiazolidine-2, 4-dione as a potential multi-target antidiabetic agent
In case of metabolic disorder like Diabetes mellitus (DM), a number of key enzymes are
abnormally expressed and hence they might be excellent targets for antidiabetic drug …
abnormally expressed and hence they might be excellent targets for antidiabetic drug …
Research progress in biological activities of succinimide derivatives
Z Zhao, J Yue, X Ji, M Nian, K Kang, H Qiao… - Bioorganic …, 2021 - Elsevier
Succinimides are well recognized heterocyclic compounds in drug discovery which produce
diverse therapeutically related applications in pharmacological practices. Researches in …
diverse therapeutically related applications in pharmacological practices. Researches in …
Green synthesis, antibacterial and antifungal evaluation of new thiazolidine-2, 4-dione derivatives: molecular dynamic simulation, POM study and identification of …
In this study, a series of thiazolidine-2, 4-dione derivatives 3a–i were synthesized and
evaluated for antibacterial activity against Gram-positive and Gram-negative strains of …
evaluated for antibacterial activity against Gram-positive and Gram-negative strains of …
Natural products-based drugs: potential therapeutics against Alzheimer's disease and other neurological disorders
Alzheimer's disease (AD) and dementia are disorders of the aging population and becoming
major health care burden worldwide due to unavailability of complete therapy. AD is the …
major health care burden worldwide due to unavailability of complete therapy. AD is the …