Environmental enteric dysfunction pathways and child stunting: A systematic review

KM Harper, M Mutasa, AJ Prendergast… - PLoS neglected …, 2018 - journals.plos.org
Background Environmental enteric dysfunction (EED) is commonly defined as an acquired
subclinical disorder of the small intestine, characterized by villous atrophy and crypt …

Environmental enteric dysfunction: an overview

RJ Crane, KDJ Jones… - Food and nutrition …, 2015 - journals.sagepub.com
Background Environmental enteric dysfunction (EED) refers to an incompletely defined
syndrome of inflammation, reduced absorptive capacity, and reduced barrier function in the …

Causal pathways from enteropathogens to environmental enteropathy: findings from the MAL-ED birth cohort study

MN Kosek, T Ahmed, Z Bhutta, L Caulfield… - …, 2017 - thelancet.com
Background Environmental enteropathy (EE), the adverse impact of frequent and numerous
enteric infections on the gut resulting in a state of persistent immune activation and altered …

Stunting is characterized by chronic inflammation in Zimbabwean infants

AJ Prendergast, S Rukobo, B Chasekwa, K Mutasa… - PloS one, 2014 - journals.plos.org
Background Stunting affects one-third of children in develo** countries, but the causes
remain unclear. We hypothesized that enteropathy leads to low-grade inflammation, which …

Biomarkers of environmental enteropathy, inflammation, stunting, and impaired growth in children in northeast Brazil

RL Guerrant, AM Leite, R Pinkerton, PHQS Medeiros… - PloS one, 2016 - journals.plos.org
Critical to the design and assessment of interventions for enteropathy and its developmental
consequences in children living in impoverished conditions are non-invasive biomarkers …

Environmental enteropathy, oral vaccine failure and growth faltering in infants in Bangladesh

C Naylor, M Lu, R Haque, D Mondal, E Buonomo… - …, 2015 - thelancet.com
Background Environmental enteropathy (EE) is a subclinical enteric condition found in low-
income countries that is characterized by intestinal inflammation, reduced intestinal …

[HTML][HTML] Diarrheal diseases

GT Keusch, CF Walker, JK Das, S Horton, D Habte - 2016 - europepmc.org
The annual number of deaths from diarrheal diseases among the 0–4 year age group in low-
and middle-income countries (LMICs) has dropped by 89 percent, from 4.6 million in 1980 to …

Assessment of environmental enteropathy in the MAL-ED cohort study: theoretical and analytic framework

M Kosek, RL Guerrant, G Kang, Z Bhutta… - Clinical Infectious …, 2014 - academic.oup.com
Individuals in the develo** world live in conditions of intense exposure to enteric
pathogens due to suboptimal water and sanitation. These environmental conditions lead to …

Linear growth faltering in infants is associated with Acidaminococcus sp. and community-level changes in the gut microbiota

EK Gough, DA Stephens, EEM Moodie, AJ Prendergast… - Microbiome, 2015 - Springer
Background Chronic malnutrition, termed stunting, is defined as suboptimal linear growth,
affects one third of children in develo** countries, and leads to increased mortality and …

Risk factors of stunting among children living in an urban slum of Bangladesh: findings of a prospective cohort study

MM Islam, KI Sanin, M Mahfuz, AMS Ahmed… - BMC public health, 2018 - Springer
Background Bangladesh is one of the 20 countries with highest burden of stunting globally.
A large portion (around 2.2 million) of the population dwells in the slum areas under severe …