The NINCDS–ADRDA and the DSM-IV-TR criteria for Alzheimer's disease (AD) are the
prevailing diagnostic standards in research; however, they have now fallen behind the …

More than 25 million people in the world today are affected by dementia, most suffering from
Alzheimer's disease. In both developed and develo** nations, Alzheimer's disease has …

Context Many observational studies have shown that physical activity reduces the risk of
cognitive decline; however, evidence from randomized trials is lacking. Objective To …

The modern era of drug development for A lzheimer's disease began with the proposal of
the cholinergic hypothesis of memory impairment and the 1984 research criteria for A …

Currently, enhancement of cholinergic neurotransmission via cholinesterase inhibitors
represents the main available approach to treat cognitive and behavioural symptoms of the …

Objectives: Cognitive decline is often associated with the aging process. Ashwagandha
(Withania somnifera (L.) Dunal) has long been used in the traditional Ayurvedic system of …

In the 12 years since the publication of the first Consensus Paper of the WFSBP on
biomarkers of neurodegenerative dementias, enormous advancement has taken place in …

There is an increasing interest in nootropic drugs for the treatment of CNS disorders. Since
the last meta-analysis of the clinical efficacy of piracetam, more information has …

A 24-week, randomized, double-blind placebo-controlled study was carried out to test the
feasibility of using omega-3 polyunsaturated fatty acids (PUFAs) monotherapy in people with …

Background Mild cognitive impairment (MCI) refers to a transitional zone between normal
ageing and dementia. Despite the uncertainty regarding the definition of MCI as a clinical …