[HTML][HTML] Liquid biopsy in the clinical management of cancers

HY Ho, KS Chung, CM Kan, SC Wong - International Journal of Molecular …, 2024 - mdpi.com
Liquid biopsy, a noninvasive diagnosis that examines circulating tumor components in body
fluids, is increasingly used in cancer management. An overview of relevant literature …

Recent advances and future perspectives in the therapeutics of prostate cancer

GL Varaprasad, VK Gupta, K Prasad, E Kim… - … Hematology & Oncology, 2023 - Springer
Prostate cancer (PC) is one of the most common cancers in males and the fifth leading
reason of death. Age, ethnicity, family history, and genetic defects are major factors that …

Aptamers as potential therapeutic tools for ovarian cancer: Advancements and challenges

W Szymanowski, A Szymanowska, A Bielawska… - Cancers, 2023 - mdpi.com
Simple Summary Aptamers are versatile molecules for cancer treatment. They can be used
to target specific molecules, conjugated to additional nucleic acid moieties or payloads. In …

Research progress of Claudin-low breast cancer

C Pan, A Xu, X Ma, Y Yao, Y Zhao, C Wang… - Frontiers in …, 2023 - frontiersin.org
Claudin-low breast cancer (CLBC) is a subgroup of breast cancer discovered at the
molecular level in 2007. Claudin is one of the primary proteins that make up tight junctions …

Aptamer-functionalized quasi-ZIF-67@ methylene blue hybrid nanoprobes for the electrochemical aptasensing of epithelial cancer biomarkers

Y Ma, X Shi, Y Ding, X Zhang, J Lu, D Sun - Chemical Engineering Journal, 2024 - Elsevier
The cell surface protein epithelial cell adhesion molecule (EpCAM) has oncogenic effects,
and its overexpression is strongly correlated with tumor development. Here, an …

Tumor microenvironment-induced tumor cell plasticity: relationship with hypoxic stress and impact on tumor resistance

RF Zaarour, M Ribeiro, B Azzarone, S Kapoor… - Frontiers in …, 2023 - frontiersin.org
The role of tumor interaction with stromal components during carcinogenesis is crucial for
the design of efficient cancer treatment approaches. It is widely admitted that tumor hypoxic …

Molecular analysis of XPO1 inhibitor and gemcitabine–nab‐paclitaxel combination in KPC pancreatic cancer mouse model

MH Uddin, MN Al‐Hallak, HY Khan… - Clinical and …, 2023 - Wiley Online Library
Background The majority of pancreatic ductal adenocarcinoma (PDAC) patients experience
disease progression while on treatment with gemcitabine and nanoparticle albumin‐bound …

Precise Capture and Dynamic Release of Circulating Liver Cancer Cells with Dual‐Histidine‐Based Cell Imprinted Hydrogels

W Sun, X You, X Zhao, X Zhang, C Yang… - Advanced …, 2024 - Wiley Online Library
Circulating tumor cells (CTCs) detection presents significant advantages in diagnosing liver
cancer due to its noninvasiveness, real‐time monitoring, and dynamic tracking. However …

TMIGD1: Emerging functions of a tumor supressor and adhesion receptor

EM Thüring, C Hartmann, YA Schwietzer, K Ebnet - Oncogene, 2023 - nature.com
The development of multicellular organisms depends on cell adhesion molecules (CAMs)
that connect cells to build tissues. The immunoglobulin superfamily (IgSF) constitutes one of …

PD-1 blockade does not improve efficacy of EpCAM-directed CAR T-cell in lung cancer brain metastasis

J Blobner, L Dengler, C Eberle, JJ Herold, T Xu… - Cancer Immunology …, 2024 - Springer
Background Lung cancer brain metastasis has a devastating prognosis, necessitating
innovative treatment strategies. While chimeric antigen receptor (CAR) T-cell show promise …