Treatment‐resistant depression: definition, prevalence, detection, management, and investigational interventions

RS McIntyre, M Alsuwaidan, BT Baune, M Berk… - World …, 2023 - Wiley Online Library
Treatment‐resistant depression (TRD) is common and associated with multiple serious
public health implications. A consensus definition of TRD with demonstrated predictive utility …

New and emerging treatments for major depressive disorder

C Njenga, PP Ramanuj, FJC de Magalhães, HA Pincus - bmj, 2024 - bmj.com
Major depressive disorder (MDD) affects a substantial portion of the population; however,
much is still unknown about the pathophysiology of this disorder. Treatment resistance …

Functional MRI markers for treatment-resistant depression: Insights and challenges

V Kotoula, JW Evans, C Punturieri, SC Johnson… - Progress in brain …, 2023 - Elsevier
Imaging studies of treatment-resistant depression (TRD) have examined brain activity,
structure, and metabolite concentrations to identify critical areas of investigation in TRD as …

Transcranial magnetic stimulation and ketamine: implications for combined treatment in depression

W Dębowska, M Więdłocha, M Dębowska… - Frontiers in …, 2023 - frontiersin.org
Drug-resistant mental disorders, particularly treatment-resistant depression, pose a
significant medical and social problem. To address this challenge, modern psychiatry is …

Intermittent theta burst stimulation (iTBS)-induced changes of resting-state brain entropy (BEN)

PS Liu, DH Song, XP Deng, YQ Shang, Q Ge, Z Wang… - bioRxiv, 2024 - biorxiv.org
Intermittent theta burst stimulation (iTBS) is a novel protocol of repetitive transcranial
magnetic stimulation (rTMS). While iTBS has shown better therapeutic effects for depression …

Comparative study about the therapeutic effect of cTBS and rTMS in the treatment of auditory verbal hallucinations in schizophrenia

X Gao, Y Ni, W Hu, G Wang, X He - Postgraduate Medical …, 2024 - academic.oup.com
Objective This study aims to compare the therapeutic effects of repetitive transcranial
magnetic stimulation (rTMS) and continuous theta-burst stimulation (cTBS) treatment in …

[HTML][HTML] Neurocognitive Effects of Theta Burst Stimulation for Treatment-Resistant Depression in Adults: A Systematic Review and Recommendations for Future …

M Hutnyan, SM McClintock - Transcranial Magnetic Stimulation, 2025 - Elsevier
Repetitive transcranial magnetic stimulation (rTMS) was cleared by the US Food and Drug
Administration (FDA) in 2008 as a treatment for major depressive disorder (MDD). Since …

Efectos neuromoduladores, funcionales y estructurales de la estimulación theta-burst intermitente y su relación con la respuesta clínica en pacientes con enfermedad …

R Rashid Abdul Rahim Lopez - 2024 - rodin.uca.es
La estimulación theta-burst intermitente (iTBS) es un patrón de estimulación magnética
transcraneal repetitiva (rTMS) excitadora que ha puesto de manifiesto resultados …

Association between Levels of Cortical Excitation/Inhibition and Clinical Response to Theta Burst Stimulation in Individuals with Major Depressive Disorder

N Kiaee - 2023 - repository.library.carleton.ca
Introduction. Theta burst stimulation (TBS), a form of repetitive transcranial magnetic
stimulation (TMS), is an effective treatment for major depressive disorder (MDD). TBS is …

BRIGhTMIND trial-motivating mechanism of action analysis plan: Magnetic Resonance Spectroscopy

H Oh - 2023 - rdmc.nottingham.ac.uk
This is the acquired spectra processing and statistical analysis plans for the BRIGhTMIND
clinical trial. It demonstrates hypotheses related with magnetic resonance spectroscopy …