Comparative analyses of zebrafish anxiety-like behavior using conflict-based novelty tests

EV Kysil, DA Meshalkina, EE Frick, DJ Echevarria… - Zebrafish, 2017 - liebertpub.com
Modeling of stress and anxiety in adult zebrafish (Danio rerio) is increasingly utilized in
neuroscience research and central nervous system (CNS) drug discovery. Representing the …

Impact of pharmaceutical products on zebrafish: An effective tool to assess aquatic pollution

M Porretti, F Arrigo, G Di Bella, C Faggio - Comparative Biochemistry and …, 2022 - Elsevier
Overuse of pharmaceuticals products (PPs) and sometimes ineffective wastewater
purification systems have led to the accumulation of these residues in aquatic systems …

Towards more compassionate wildlife research through the 3Rs principles: Moving from invasive to non‐invasive methods

MA Zemanova - Wildlife Biology, 2020 - Wiley Online Library
Research in ecology and wildlife biology remains crucial for increasing our knowledge and
improving species management and conservation in the midst of the current biodiversity …

[HTML][HTML] Effects of fluoxetine on fish: What do we know and where should we focus our efforts in the future?

D Correia, I Domingues, M Faria, M Oliveira - Science of the Total …, 2023 - Elsevier
Fluoxetine is one of the most studied and detected selective serotonin reuptake inhibitors in
the aquatic environment, found at concentrations ranging from ng/L to μg/L. Its presence in …

[HTML][HTML] Resveratrol and depression in animal models: a systematic review of the biological mechanisms

A Moore, J Beidler, MY Hong - Molecules, 2018 - mdpi.com
Depression is currently treated by pharmacotherapies that can elicit debilitating side effects
for patients. Novel treatment options with limited side effects are currently being researched …

[HTML][HTML] Understanding how stress responses and stress-related behaviors have evolved in zebrafish and mammals

MS de Abreu, KA Demin, ACVV Giacomini… - Neurobiology of …, 2021 - Elsevier
Stress response is essential for the organism to quickly restore physiological homeostasis
disturbed by various environmental insults. In addition to well-established physiological …

Proximate causes and ultimate effects of common antidepressants, fluoxetine and venlafaxine, on fish behavior

A Salahinejad, A Attaran, D Meuthen… - Science of the Total …, 2022 - Elsevier
Antidepressant (AD) drugs are widely prescribed for the treatment of psychiatric disorders,
including depression and anxiety disorders. The continuous use of ADs causes significant …

Fluoxetine and diazepam acutely modulate stress induced-behavior

ACVV Giacomini, MS Abreu, LV Giacomini… - Behavioural Brain …, 2016 - Elsevier
Drug residue contamination in aquatic ecosystems has been studied extensively, but the
behavioral effects exerted by the presence of these drugs are not well known. Here, we …

Effects of pharmaceuticals present in aquatic environment on Phase I metabolism in fish

V Burkina, V Zlabek, G Zamaratskaia - Environmental toxicology and …, 2015 - Elsevier
The fate of pharmaceuticals in aquatic environments is an issue of concern. Current
evidence indicates that the risks to fish greatly depend on the nature and concentrations of …

[HTML][HTML] A cross-species comparative approach to assessing multi-and transgenerational effects of endocrine disrupting chemicals

B Robaire, G Delbes, JA Head, VL Marlatt… - Environmental …, 2022 - Elsevier
A wide range of chemicals have been identified as endocrine disrupting chemicals (EDCs)
in vertebrate species. Most studies of EDCs have focused on exposure of both male and …