Bone is a mineralized and elastic connective tissue that provides fundamental functions in
the human body, including mechanical support to the muscles and joints, protection of vital …

The skeletal system is essential for preserving body structure and facilitating mobility;
however, bone diseases frequently result in significant disabilities, necessitating the …

The improved corrosion resistance, osteogenic activity, and antibacterial ability are the key
factors for promoting the large-scale clinical application of magnesium (Mg)-based implants …

Background and objective Bone loss occurs in several inflammatory diseases because of
chronic persistent inflammation that activates osteoclasts (OCs) to increase bone resorption …

Chronic periapical periodontitis (CAP) is a typical oral disease in which periodontal
inflammation caused by an odontogenic infection eventually leads to bone loss …

Discoveries in the last few years have emphasized the existence of an enormous breadth of
communication between bone and the immune system in maintaining skeletal homeostasis …

Infection and aseptic loosening caused by bacteria and poor osseointegration remain
serious challenges for orthopedic implants. The advanced surface modification of implants is …

Excessive bone erosion by osteoclasts is associated with osteoporosis, rheumatoid arthritis,
and periprosthetic osteolysis. Targeting osteoclasts may serve as an effective treatment for …

Abstract Non-communicable diseases (NCDs), including cardiovascular diseases, cancer,
metabolic diseases, and skeletal diseases, pose significant challenges to public health …

Polyetheretherketone (PEEK) has been widely used as orthopedic implants, but the poor
antimicrobial and osseointegration properties hinder its advanced clinical applications. Most …