Computer aided drug design: success and limitations

M Hassan Baig, K Ahmad, S Roy… - Current …, 2016 - ingentaconnect.com
Over the last few decades, computer-aided drug design has emerged as a powerful
technique playing a crucial role in the development of new drug molecules. Structure-based …

A new class of inhibitors of the AraC family virulence regulator Vibrio cholerae ToxT

AK Woodbrey, EO Onyango, M Pellegrini… - Scientific Reports, 2017 - nature.com
Vibrio cholerae is responsible for the diarrheal disease cholera that infects millions of
people worldwide. While vaccines protecting against cholera exist, and oral rehydration …

[HTML][HTML] In silico screening of antibacterial compounds from herbal sources against Vibrio cholerae

S Perveen, HS Chaudhary - Pharmacognosy magazine, 2015 - ncbi.nlm.nih.gov
Background: The prolonged use of antibiotic viz., tetracycline, quinolones, ampicillin, etc., to
reduce the infection of cholera, may failed due to the emergence of new Vibrio cholerae …

MicroRNA analysis of NCI-60 human cancer cells indicates that miR-720 and miR-887 are potential therapeutic biomarkers for breast cancer

Z Lv, S Wang, W Zhao, N He - Drug Discoveries & Therapeutics, 2020 - jstage.jst.go.jp
MicroRNAs (miRNAs) play a vital role in many biological processes, including cell growth,
differentiation, apoptosis, development, differentiation, and carcinogenesis. Since miRNAs …

Targeting aphA : a new high-throughput screening assay identifies compounds that reduce prime virulence factors of Vibrio cholerae

G Bolger, S Roy, VA Zapol'skii… - Journal of Medical …, 2016 - microbiologyresearch.org
A high-throughput screening (HTS) assay was developed for identifying compounds with
inhibitory effect on aphA, one of the key regulators positively controlling Vibrio cholerae …

Study of intra–inter species protein–protein interactions for potential drug targets identification and subsequent drug design for Escherichia coli O104:H4 C277-11

SI Mondal, Z Mahmud, M Elahi, A Akter, NA Jewel… - In Silico …, 2017 - Springer
Protein–protein interaction (PPI) and host–pathogen interactions (HPI) proteomic analysis
has been successfully practiced for potential drug target identification in pathogenic …

MODERN PROBLEMS AND PROSPECTS IN THE DEVELOPMENT OF THE THERAPY OF CHOLERA

NA Selyanskaya - Epidemiology and Infectious Diseases, 2019 - journals.eco-vector.com
The spread of V. cholerae strains with multiple antibiotic resistance limits the choice of
effective means of etiotropic therapy for cholera, emphasizing the importance of finding ways …

[HTML][HTML] Изучение антибактериальной активности производного фенилуксусной кислоты в отношении возбудителя холеры

НА Селянская, СН Головин - Антибиотики и химиотерапия, 2020 - cyberleninka.ru
Изучена активность in vitro и in vivo производного фенилуксусной кислоты-
диклофенака-в отношении штаммов V. cholerae О1 El Tor и образованных ими …

[PDF][PDF] СоВреМеннЫе ПроБЛеМЫ и ПерСПеКТиВЫ СоВерШенСТВоВаниЯ ТераПии ХоЛерЫ

НА Селянская - Эпидемиология и инфекционные болезни, 2019 - scholar.archive.org
Распространение штаммов V. cholerae, обладающих множественной
антибиотикорезистентностью, ограничивает выбор эффективных средств …