Metabolomics uses advanced analytical chemistry techniques to enable the high-throughput
characterization of metabolites from cells, organs, tissues, or biofluids. The rapid growth in …

Background Emerging evidence demonstrates that gut dysbiosis is implicated in the
pathogenesis of chronic kidney disease (CKD) with underlying mechanisms involving …

During chronic kidney disease (CKD), typical alterations in the gut microbiota are observed.
The kidney no longer plays the role of the main excretory organ as this function is performed …

In chronic kidney disease (CKD), impaired kidney function results in accumulation of uremic
toxins, which exert deleterious biological effects and contribute to inflammation and …

Background There is mounting evidence that individuals with kidney disease and kidney
stones have an abnormal gut microbiota composition. No studies to date have summarised …

Background: A bidirectional kidney–gut axis was described in patients with chronic kidney
disease (CKD). On the one hand, gut dysbiosis could promote CKD progression, but on the …

Purpose Diabesity, the combination of obesity and type 2 diabetes, is an ever-growing
global health burden. Diabesity-associated dysbiosis of the intestinal microbiome has …

Huangkui capsule (HKC), a traditional Chinese medicine, has been used for medication of
kidney diseases, including diabetic nephropathy (DN). The current study aimed to evaluate …

Proton pump inhibitors (PPI) are an invaluable therapy option for acid related diseases;
however, PPI therapy is also linked to a series of side effects in cirrhosis, such as …

Chronic kidney disease (CKD) has been associated with changes in gut microbial ecology,
or “dysbiosis,” which may contribute to disease progression. Recent studies have focused …