RNA structural motifs: building blocks of a modular biomolecule

DK Hendrix, SE Brenner, SR Holbrook - Quarterly reviews of …, 2005 - cambridge.org
1. Introduction 2222. What is an RNA motif? 2222.1 Sequence vs. structural motifs 2222.2
RNA structural motifs 2232.3 RNA structural elements vs. motifs 2232.4 Specific recognition …

Molecular engineering of guanine-rich sequences: Z-DNA, DNA triplexes, and G-quadruplexes

O Doluca, JM Withers, VV Filichev - Chemical reviews, 2013 - ACS Publications
Guanine's array of hydrogen bond donors and acceptors lead it to take part in structures as
diverse as B-DNA, Z-DNA, hairpins, cruciforms, triplexes, and G-quadruplexes; these …

Sensing of viral and endogenous RNA by ZBP 1/DAI induces necroptosis

J Maelfait, L Liverpool, A Bridgeman, KB Ragan… - The EMBO …, 2017 - embopress.org
Nucleic acids are potent triggers for innate immunity. Double‐stranded DNA and RNA adopt
different helical conformations, including the unusual Z‐conformation. Z‐DNA/RNA is …

Double-stranded RNA under force and torque: similarities to and striking differences from double-stranded DNA

J Lipfert, GM Skinner, JM Keegstra… - Proceedings of the …, 2014 - National Acad Sciences
RNA plays myriad roles in the transmission and regulation of genetic information that are
fundamentally constrained by its mechanical properties, including the elasticity and …

Structure and formation of Z-DNA and Z-RNA

JB Krall, PJ Nichols, MA Henen, Q Vicens, B Vögeli - Molecules, 2023 - mdpi.com
Despite structural differences between the right-handed conformations of A-RNA and B-
DNA, both nucleic acids adopt very similar, left-handed Z-conformations. In contrast to their …

An atypical RNA quadruplex marks RNAs as vectors for gene silencing

S Roschdi, J Yan, Y Nomura, CA Escobar… - Nature structural & …, 2022 - nature.com
The addition of poly (UG)('pUG') repeats to 3′ termini of mRNAs drives gene silencing and
transgenerational epigenetic inheritance in the metazoan Caenorhabditis elegans. pUG tails …

A left-handed RNA double helix bound by the Zα domain of the RNA-editing enzyme ADAR1

D Placido, BA Brown, K Lowenhaupt, A Rich… - Structure, 2007 - cell.com
The A form RNA double helix can be transformed to a left-handed helix, called Z-RNA.
Currently, little is known about the detailed structural features of Z-RNA or its involvement in …

Quantum dot surface engineering: toward inert fluorophores with compact size and bright, stable emission

SJ Lim, L Ma, A Schleife, AM Smith - Coordination Chemistry Reviews, 2016 - Elsevier
The surfaces of colloidal nanocrystals are complex interfaces between solid crystals,
coordinating ligands, and liquid solutions. For fluorescent quantum dots, the properties of …

RNA structure: the long and the short of it

SR Holbrook - Current opinion in structural biology, 2005 - Elsevier
The database of RNA structure has grown tremendously since the crystal structure analyses
of ribosomal subunits in 2000–2001. During the past year, the trend toward determining the …

Z-Form Adoption of Nucleic Acid is a Multi-Step Process Which Proceeds through a Melted Intermediate

PJ Nichols, JB Krall, MA Henen, R Welty… - Journal of the …, 2023 - ACS Publications
The left-handed Z-conformation of nucleic acids can be adopted by both DNA and RNA
when bound by Zα domains found within a variety of innate immune response proteins. Zα …