Innovative strategies for intervertebral disc regenerative medicine: from cell therapies to multiscale delivery systems
As our understanding of the physiopathology of intervertebral disc (IVD) degeneration has
improved, novel therapeutic strategies have emerged, based on the local injection of cells …
improved, novel therapeutic strategies have emerged, based on the local injection of cells …
[HTML][HTML] Total disc replacement devices: structure, material, fabrication, and properties
The intervertebral disc (IVD) is an important component of the human spine that maintains
physiological motion and distributes loads. Single-or multi-segment degeneration occurs …
physiological motion and distributes loads. Single-or multi-segment degeneration occurs …
Effect of multilevel lumbar disc arthroplasty on spine kinematics and facet joint loads in flexion and extension: a finite element analysis
H Schmidt, F Galbusera, A Rohlmann, T Zander… - European spine …, 2012 - Springer
Total disc arthroplasty (TDA) has been successfully used for monosegmental treatment in
the last few years. However, multi-level TDA led to controversial clinical results. We …
the last few years. However, multi-level TDA led to controversial clinical results. We …
Bioinspired intervertebral disc with multidirectional stiffness prepared via multimaterial additive manufacturing
Degenerative disc disease (DDD) has become a significant public health issue worldwide.
This can result in loss of spinal function affecting patient health and quality of life. Artificial …
This can result in loss of spinal function affecting patient health and quality of life. Artificial …
Lumbar disc replacement surgery—successes and obstacles to widespread adoption
SN Salzmann, N Plais, J Shue, FP Girardi - Current reviews in …, 2017 - Springer
Purpose of review Lumbar disc replacement has been a surgical alternative to fusion
surgery for the treatment of lumbar degenerative disc disease (DDD) for many years …
surgery for the treatment of lumbar degenerative disc disease (DDD) for many years …
[HTML][HTML] Operative management of lumbar degenerative disc disease
YC Lee, MGT Zotti, OL Osti - Asian spine journal, 2016 - ncbi.nlm.nih.gov
Lumbar degenerative disc disease is extremely common. Current evidence supports surgery
in carefully selected patients who have failed non-operative treatment and do not exhibit any …
in carefully selected patients who have failed non-operative treatment and do not exhibit any …
Lumbar disk arthroplasty for degenerative disk disease: literature review
Low back pain is the principal cause of long-term disability worldwide. We intend to address
one of its main causes, degenerative disk disease, a spinal condition involving degradation …
one of its main causes, degenerative disk disease, a spinal condition involving degradation …
We need to talk about lumbar total disc replacement
S Beatty - International Journal of Spine Surgery, 2018 - ijssurgery.com
Background: Replacement of a diseased lumbar intervertebral disc with an artificial device,
a procedure known as lumbar total disc replacement (LTDR), has been practiced since the …
a procedure known as lumbar total disc replacement (LTDR), has been practiced since the …
Tribological behavior of DLC-coated articulating joint implants
Coatings from diamond-like carbon (DLC) have been proven to be an excellent choice for
wear reduction in many technical applications. However, for successful adaption to the total …
wear reduction in many technical applications. However, for successful adaption to the total …
Hydrogels for nucleus replacement—facing the biomechanical challenge
Hydrogels are considered promising for disc regeneration strategies. However, it is currently
unknown whether the destruction of the natural interface between nucleus and surrounding …
unknown whether the destruction of the natural interface between nucleus and surrounding …