The thalamus is a small, bilateral structure in the diencephalon that integrates signals from
many areas of the CNS. This critical anatomical position allows the thalamus to influence …

Consciousness can be conceptualized as varying along at least two dimensions: the global
state of consciousness and the content of conscious experience. Here, we highlight the …

Abstract Models of cognitive function typically focus on the cerebral cortex and hence
overlook functional links to subcortical structures. This view does not consider the role of the …

Mounting evidence suggests that during conscious states, the electrodynamics of the cortex
are poised near a critical point or phase transition and that this near-critical behavior …

The human brain is a complex, adaptive system comprised of billions of cells with trillions of
connections. The interactions between the elements of the system oppose this seemingly …

The neurobiological mechanisms of arousal and anesthesia remain poorly understood.
Recent evidence highlights the key role of interactions between the cerebral cortex and the …

How is the massive dimensionality and complexity of the microscopic constituents of the
nervous system brought under sufficiently tight control so as to coordinate adaptive …

Microglia interact with neurons to facilitate synapse plasticity; however, signal (s)
contributing to microglia activation for synapse elimination in pathology are not fully …

The human brain displays a rich repertoire of states that emerge from the microscopic
interactions of cortical and subcortical neurons. Difficulties inherent within large-scale …

Brain recordings collected at different resolutions support distinct signatures of neural
coding, leading to scale-dependent theories of brain function. Here, we show that these …