Exosomes as a new frontier of cancer liquid biopsy
D Yu, Y Li, M Wang, J Gu, W Xu, H Cai, X Fang… - Molecular cancer, 2022 - Springer
Liquid biopsy, characterized by minimally invasive detection through biofluids such as
blood, saliva, and urine, has emerged as a revolutionary strategy for cancer diagnosis and …
blood, saliva, and urine, has emerged as a revolutionary strategy for cancer diagnosis and …
A review of exosomal isolation methods: is size exclusion chromatography the best option?
K Sidhom, PO Obi, A Saleem - International journal of molecular sciences, 2020 - mdpi.com
Extracellular vesicles (EVs) are membranous vesicles secreted by both prokaryotic and
eukaryotic cells and play a vital role in intercellular communication. EVs are classified into …
eukaryotic cells and play a vital role in intercellular communication. EVs are classified into …
A one-pot isothermal Cas12-based assay for the sensitive detection of microRNAs
The use of microRNAs as clinical cancer biomarkers is hindered by the absence of accurate,
fast and inexpensive assays for their detection in biofluids. Here we report a one-step and …
fast and inexpensive assays for their detection in biofluids. Here we report a one-step and …
Metal–organic framework-functionalized paper-based electrochemical biosensor for ultrasensitive exosome assay
X Liu, X Gao, L Yang, Y Zhao, F Li - Analytical chemistry, 2021 - ACS Publications
The exosome has emerged as a promising noninvasive biomarker for the early diagnosis of
cancer. Therefore, it is highly desirable to develop simple, inexpensive, and user-friendly …
cancer. Therefore, it is highly desirable to develop simple, inexpensive, and user-friendly …
[HTML][HTML] Progress, opportunity, and perspective on exosome isolation-efforts for efficient exosome-based theranostics
D Yang, W Zhang, H Zhang, F Zhang, L Chen, L Ma… - Theranostics, 2020 - ncbi.nlm.nih.gov
Exosomes are small extracellular vesicles with diameters of 30-150 nm. In both
physiological and pathological conditions, nearly all types of cells can release exosomes …
physiological and pathological conditions, nearly all types of cells can release exosomes …
Clinical application and detection techniques of liquid biopsy in gastric cancer
S Ma, M Zhou, Y Xu, X Gu, M Zou, G Abudushalamu… - Molecular Cancer, 2023 - Springer
Gastric cancer (GC) is one of the most common tumors worldwide and the leading cause of
tumor-related mortality. Endoscopy and serological tumor marker testing are currently the …
tumor-related mortality. Endoscopy and serological tumor marker testing are currently the …
Microfluidic strategies for the isolation and profiling of exosomes
J Bai, X Wei, X Zhang, C Wu, Z Wang, M Chen… - TrAC Trends in …, 2023 - Elsevier
Exosomes are nanoscale extracellular vesicles carrying various cargos, which play a
significant rule in intercellular communication, disease diagnosis and treatment …
significant rule in intercellular communication, disease diagnosis and treatment …
Ultrasensitive detection of circulating exosomes with a 3D-nanopatterned microfluidic chip
The performance of current microfluidic methods for exosome detection is constrained by
boundary conditions, as well as fundamental limits to microscale mass transfer and …
boundary conditions, as well as fundamental limits to microscale mass transfer and …
Microfluidics for exosome isolation and analysis: enabling liquid biopsy for personalized medicine
JC Contreras-Naranjo, HJ Wu, VM Ugaz - Lab on a Chip, 2017 - pubs.rsc.org
Exosomes, the smallest sized extracellular vesicles (∽ 30–150 nm) packaged with lipids,
proteins, functional messenger RNAs and microRNAs, and double-stranded DNA from their …
proteins, functional messenger RNAs and microRNAs, and double-stranded DNA from their …
Towards microfluidic-based exosome isolation and detection for tumor therapy
Exosomes are a class of cell-secreted, nano-sized extracellular vesicles with a bilayer
membrane structure of 30–150 nm in diameter. Their discovery and application have …
membrane structure of 30–150 nm in diameter. Their discovery and application have …