Microglia play an important role in the pathology of CNS disorders, however, there remains
significant uncertainty about the neuroprotective/degenerative role of these cells due to a …

Abstract Curcumin (1, 7-bis-(4-hydroxy-3-methoxyphenyl)-1, 6-heptadiene-3, 5dione) is a
polyphenol extracted from turmeric that has long been advocated for the treatment of a …

Glaucoma is the third leading cause of blindness worldwide and is primarily characterized
by elevated intraocular pressure (IOP). Common risk factors such as age, myopia, ocular …

Glaucoma is a multifactorial neurodegenerative disorder and one of the leading causes of
irreversible blindness globally and for which intraocular pressure is the only modifiable risk …

Glaucoma is a multifactorial neurodegenerative disease associated with retinal ganglion
cells (RGC) loss. Increasing reports of similarities in glaucoma and other neurodegenerative …

Retinal ganglion cell (RGC) replacement holds potential for restoring vision lost to optic
neuropathy. Transplanted RGCs must undergo neuroretinal integration to receive afferent …

Abstract Coenzyme Q10 (CoQ10) is a mitochondrial-targeted antioxidant with known
neuroprotective activity. Its ocular effects when co-solubilised with α–tocopherol …

Optic neuropathy is a major cause of irreversible blindness worldwide, and no effective
treatment is currently available. Secondary degeneration is believed to be the major …

This study compares four different animal models of chronic glaucoma against normal aging
over 6 months. Chronic glaucoma was induced in 138 Long–Evans rats and compared …

Purpose To review the clinical course of adult patients with acute optic neuritis over 10 years
in Hong Kong, and the results were compared with other studies among Asian and …