Microbiota and host nutrition across plant and animal kingdoms

S Hacquard, R Garrido-Oter, A González, S Spaepen… - Cell host & …, 2015 - cell.com
Plants and animals each have evolved specialized organs dedicated to nutrient acquisition,
and these harbor specific bacterial communities that extend the host's metabolic repertoire …

Gut microbiota in ulcerative colitis: insights on pathogenesis and treatment

XY Guo, XJ Liu, JY Hao - Journal of digestive diseases, 2020 - Wiley Online Library
Gut microbiota constitute the largest reservoir of the human microbiome and are an
abundant and stable ecosystem—based on its diversity, complexity, redundancy, and host …

Human genetics shape the gut microbiome

JK Goodrich, JL Waters, AC Poole, JL Sutter, O Koren… - Cell, 2014 - cell.com
Host genetics and the gut microbiome can both influence metabolic phenotypes. However,
whether host genetic variation shapes the gut microbiome and interacts with it to affect host …

Host biology in light of the microbiome: ten principles of holobionts and hologenomes

SR Bordenstein, KR Theis - PLoS biology, 2015 - journals.plos.org
Groundbreaking research on the universality and diversity of microorganisms is now
challenging the life sciences to upgrade fundamental theories that once seemed …

Metabolite-sensing receptors GPR43 and GPR109A facilitate dietary fibre-induced gut homeostasis through regulation of the inflammasome

L Macia, J Tan, AT Vieira, K Leach, D Stanley… - Nature …, 2015 - nature.com
Diet and the gut microbiota may underpin numerous human diseases. A major metabolic
product of commensal bacteria are short-chain fatty acids (SCFAs) that derive from …

Genetic determinants of the gut microbiome in UK twins

JK Goodrich, ER Davenport, M Beaumont… - Cell host & …, 2016 - cell.com
Studies in mice and humans have revealed intriguing associations between host genetics
and the microbiome. Here we report a 16S rRNA-based analysis of the gut microbiome in …

[HTML][HTML] Diet dominates host genotype in sha** the murine gut microbiota

RN Carmody, GK Gerber, JM Luevano, DM Gatti… - Cell host & …, 2015 - cell.com
Mammals exhibit marked interindividual variations in their gut microbiota, but it remains
unclear if this is primarily driven by host genetics or by extrinsic factors like dietary intake. To …

The effect of host genetics on the gut microbiome

MJ Bonder, A Kurilshikov, EF Tigchelaar, Z Mujagic… - Nature …, 2016 - nature.com
The gut microbiome is affected by multiple factors, including genetics. In this study, we
assessed the influence of host genetics on microbial species, pathways and gene ontology …

Host genetic variation impacts microbiome composition across human body sites

R Blekhman, JK Goodrich, K Huang, Q Sun… - Genome biology, 2015 - Springer
Background The composition of bacteria in and on the human body varies widely across
human individuals, and has been associated with multiple health conditions. While microbial …

Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota

J Wang, LB Thingholm, J Skiecevičienė, P Rausch… - Nature …, 2016 - nature.com
Human gut microbiota is an important determinant for health and disease, and recent
studies emphasize the numerous factors sha** its diversity. Here we performed a genome …