The contribution of the immune system to idiopathic pulmonary fibrosis (IPF) remains poorly
understood. While most sources agree that IPF does not result from a primary …

Systemic sclerosis (SSc) has the highest cause-specific mortality of all the connective tissue
diseases, and the aetiology of this complex and heterogeneous condition remains an …

Rationale: Idiopathic pulmonary fibrosis (IPF) involves the accumulation of α-smooth muscle
actin–expressing myofibroblasts arising from interactions with soluble mediators such as …

Idiopathic pulmonary fibrosis (IPF) is a chronic, debilitating, fibrotic lung disease leading to
respiratory failure and ultimately to death. Being the prototype of interstitial lung diseases …

We have previously shown that endoplasmic reticulum stress (ER stress) represses the
PTEN inducible kinase 1 (PINK1) in lung type II alveolar epithelial cells (AECII) reducing …

Idiopathic pulmonary fibrosis (IPF) represents a chronic progressive fibrotic interstitial lung
disease of unknown cause with an ominous prognosis. It remains an unprecedent clinical …

Idiopathic pulmonary fibrosis (IPF) is a fatal chronic interstitial lung disease (ILD) that affects
lung mechanical functions and gas exchange. IPF is caused by increased fibroblast activity …

Convincing evidence has emerged demonstrating that impairment of mitochondrial function
is critically important in regulating alveolar epithelial cell (AEC) programmed cell death …

Excessive neutrophil extracellular trap (NET) formation may contribute to polymyositis (PM)‐
associated interstitial lung diseases (ILD), but the underlying mechanism is not fully …

Abstract Purpose of Review Idiopathic pulmonary fibrosis (IPF) is the most common form of
interstitial lung disease of unknown etiopathogenesis with mean survival of 3–5 years and …