Synaptic abnormalities are a cardinal feature of Alzheimer's disease (AD) that are known to
arise as the disease progresses. A growing body of evidence suggests that pathological …

Abstract Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterised
by deficits in social communication and restricted or repetitive behaviours. The clinical …

Cognitive decline in chronic diabetic patients is a less investigated topic. Diabetes and
obesity are among the modifiable risk factors for Alzheimer's disease (AD), the most …

Background Animal studies show that peripheral inflammatory stimuli may activate
microglial cells in the brain implicating an important role for microglia in sepsis-associated …

The proportion of advanced age patients undergoing surgical procedures is on the rise
owing to advancements in surgical and anesthesia technologies as well as an overall aging …

Worldwide, and especially in Western civilizations, most of the staple diets contain high
amounts of fat and refined carbohydrates, leading to an increasing number of obese …

The world⿿ s population is steadily ageing and as a result, health conditions related to
ageing, such as dementia, have become a major public health concern. In 2001, it was …

Multiple sclerosis (MS) is a chronic disease that is characterized by demyelination and
axonal damage in the central nervous system. Cognitive deficits are recognized as one of …

Abstract Post-Operative Cognitive Dysfunction (POCD) is a highly prevalent condition with
significant clinical, social and financial impacts for patients and their communities. The …

Cytokines are key regulatory mediators involved in the host response to immunological
challenges, but also play a critical role in the communication between the immune and the …