The mosquito holobiont: fresh insight into mosquito-microbiota interactions
The holobiont concept was first developed for coral ecosystems but has been extended to
multiple organisms, including plants and other animals. Studies on insect-associated …
multiple organisms, including plants and other animals. Studies on insect-associated …
Host-directed therapies for infectious diseases: current status, recent progress, and future prospects
Despite extensive global efforts in the fight against killer infectious diseases, they still cause
one in four deaths worldwide and are important causes of long-term functional disability …
one in four deaths worldwide and are important causes of long-term functional disability …
Mosquito vector competence for dengue is modulated by insect-specific viruses
Aedes aegypti and A. albopictus mosquitoes are the main vectors for dengue virus (DENV)
and other arboviruses, including Zika virus (ZIKV). Understanding the factors that affect …
and other arboviruses, including Zika virus (ZIKV). Understanding the factors that affect …
[HTML][HTML] Identification of Zika virus and dengue virus dependency factors using functional genomics
G Savidis, WM McDougall, P Meraner, JM Perreira… - Cell reports, 2016 - cell.com
The flaviviruses dengue virus (DENV) and Zika virus (ZIKV) are severe health threats with
rapidly expanding ranges. To identify the host cell dependencies of DENV and ZIKV, we …
rapidly expanding ranges. To identify the host cell dependencies of DENV and ZIKV, we …
The 5′ and 3′ untranslated regions of the flaviviral genome
Flaviviruses are enveloped arthropod-borne viruses with a single-stranded, positive-sense
RNA genome that can cause serious illness in humans and animals. The 11 kb 5′ capped …
RNA genome that can cause serious illness in humans and animals. The 11 kb 5′ capped …
Ribosomal frameshifting and transcriptional slippage: From genetic steganography and cryptography to adventitious use
Genetic decoding is not 'frozen'as was earlier thought, but dynamic. One facet of this is
frameshifting that often results in synthesis of a C-terminal region encoded by a new frame …
frameshifting that often results in synthesis of a C-terminal region encoded by a new frame …
Genome sequence of the Asian Tiger mosquito, Aedes albopictus, reveals insights into its biology, genetics, and evolution
The Asian tiger mosquito, Aedes albopictus, is a highly successful invasive species that
transmits a number of human viral diseases, including dengue and Chikungunya fevers …
transmits a number of human viral diseases, including dengue and Chikungunya fevers …
[HTML][HTML] Vertical transmission of Zika virus in Aedes aegypti mosquitoes
S Thangamani, J Huang, CE Hart… - The American journal …, 2016 - ncbi.nlm.nih.gov
Previous experimental studies have demonstrated that a number of mosquito-borne
flavivirus pathogens are vertically transmitted in their insect vectors, providing a mechanism …
flavivirus pathogens are vertically transmitted in their insect vectors, providing a mechanism …
The microbiome modulates arbovirus transmission in mosquitoes
Highlights•Complex interactions occur within the mosquito holobiome that profoundly alter
the phenotype of the host.•Bacteria can enhance or suppress arbovirus transmission in …
the phenotype of the host.•Bacteria can enhance or suppress arbovirus transmission in …
Aedes spp. and Their Microbiota: A Review
Aedes spp. are a major public health concern due to their ability to be efficient vectors of
dengue, Chikungunya, Zika, and other arboviruses. With limited vaccines available and no …
dengue, Chikungunya, Zika, and other arboviruses. With limited vaccines available and no …