Design of therapeutic biomaterials to control inflammation

Z Tu, Y Zhong, H Hu, D Shao, R Haag… - Nature Reviews …, 2022 - nature.com
Inflammation plays an important role in the response to danger signals arising from damage
to our body and in restoring homeostasis. Dysregulated inflammatory responses occur in …

Stimuli-responsive nanocarriers for drug delivery, tumor imaging, therapy and theranostics

P Mi - Theranostics, 2020 - pmc.ncbi.nlm.nih.gov
In recent years, much progress has been motivated in stimuli-responsive nanocarriers,
which could response to the intrinsic physicochemical and pathological factors in diseased …

Nanomaterial-based contrast agents

JC Hsu, Z Tang, OE Eremina, AM Sofias… - Nature Reviews …, 2023 - nature.com
Medical imaging, which empowers the detection of physiological and pathological
processes within living subjects, has a vital role in both preclinical and clinical diagnostics …

Nanomaterials for in vivo imaging

BR Smith, SS Gambhir - Chemical reviews, 2017 - ACS Publications
In vivo imaging, which enables us to peer deeply within living subjects, is producing
tremendous opportunities both for clinical diagnostics and as a research tool. Contrast …

Versatile types of organic/inorganic nanohybrids: from strategic design to biomedical applications

N Zhao, L Yan, X Zhao, X Chen, A Li, D Zheng… - Chemical …, 2018 - ACS Publications
Organic/inorganic nanohybrids have attracted widespread interests due to their favorable
properties and promising applications in biomedical areas. Great efforts have been made to …

Engineering of inorganic nanoparticles as magnetic resonance imaging contrast agents

D Ni, W Bu, EB Ehlerding, W Cai, J Shi - Chemical Society Reviews, 2017 - pubs.rsc.org
Magnetic resonance imaging (MRI) is a highly valuable non-invasive imaging tool owing to
its exquisite soft tissue contrast, high spatial resolution, lack of ionizing radiation, and wide …

[HTML][HTML] Recent advances in engineering iron oxide nanoparticles for effective magnetic resonance imaging

Z Zhao, M Li, J Zeng, L Huo, K Liu, R Wei, K Ni, J Gao - Bioactive materials, 2022 - Elsevier
Iron oxide nanoparticle (IONP) with unique magnetic property and high biocompatibility
have been widely used as magnetic resonance imaging (MRI) contrast agent (CA) for long …

Restoration of spinal cord biophysical microenvironment for enhancing tissue repair by injury-responsive smart hydrogel

C Fan, W Yang, L Zhang, H Cai, Y Zhuang, Y Chen… - Biomaterials, 2022 - Elsevier
Spinal cord injury (SCI) represents a central nervous system disaster, resulting in the
destruction of spinal cord structure and function and the formation of an adverse …

Recent advances in superparamagnetic iron oxide nanoparticles (SPIONs) for in vitro and in vivo cancer nanotheranostics

G Kandasamy, D Maity - International journal of pharmaceutics, 2015 - Elsevier
Recently superparamagnetic iron oxide nanoparticles (SPIONs) have been extensively used
in cancer therapy and diagnosis (theranostics) via magnetic targeting, magnetic resonance …

MMP-responsive 'smart'drug delivery and tumor targeting

Q Yao, L Kou, Y Tu, L Zhu - Trends in pharmacological sciences, 2018 - cell.com
Matrix metalloproteinases (MMPs) are major extracellular enzymes involved in cancer
initiation, progression, and metastasis. MMPs are widely used as cancer biomarkers and …