Primary lung cancer remains the most common malignancy after non-melanocytic skin
cancer, and deaths from lung cancer exceed those from any other malignancy worldwide [1] …

In contrast to solid cancers, which often require genetic modifications and complex cellular
reprogramming for effective metastatic dissemination, leukaemic cells uniquely possess the …

Diagnosis of tumour type allows prognostication and triage for biomarker testing (see the
Supplementary Material Section 3 and Supplementary Figure S1, available at https://doi …

Lung cancer is the leading cause of cancer mortality worldwide with 1.8 million newly
diagnosed cases, or 13% of all cancers diagnosed, in 2012 [1]. The worldwide numbers are …

Stage classification provides a nomenclature about the anatomic extent of a cancer; a
consistent language provides the ability to communicate about a specific patient and about …

In 2012, lung cancer was the most frequently diagnosed cancer and the leading cause of
cancer death in male populations. Among females, lung cancer was the leading cause of …

1. In KEYNOTE-189, patients with metastatic non-squamous NSCLC, PS 0-1, without
sensitising EGFR or ALK mutations, were randomised to receive pemetrexed and a platinum …

The most recent version of the European Society for Medical Oncology (ESMO) Clinical
Practice Guidelines for the diagnosis, treatment and follow-up of metastatic non-small-cell …

Answer questions and earn CME/CNE The revision for the eighth edition of the tumor, node,
and metastasis (TNM) classification of lung cancer was based on analyses of the …

Cell division drives somatic evolution but is challenging to quantify. We developed a
framework to count cell divisions with DNA replication-related mutations in polyguanine …