The promising role of miR-21 as a cancer biomarker and its importance in RNA-based therapeutics

D Bautista-Sánchez, C Arriaga-Canon… - … therapy Nucleic acids, 2020 - cell.com
MicroRNAs are small noncoding transcripts that posttranscriptionally regulate gene
expression via base-pairing complementarity. Their role in cancer can be related to tumor …

Cell‐to‐cell communication: microRNAs as hormones

R Bayraktar, K Van Roosbroeck… - Molecular oncology, 2017 - Wiley Online Library
Mammalian cells can release different types of extracellular vesicles (EVs), including
exosomes, microvesicles, and apoptotic bodies. Accumulating evidence suggests that EVs …

How VEGF-A and its splice variants affect breast cancer development–clinical implications

H Al Kawas, I Saaid, P Jank, CC Westhoff, C Denkert… - Cellular Oncology, 2022 - Springer
Background Altered expression levels and structural variations in the vascular endothelial
growth factor (VEGF) have been found to play important roles in cancer development and to …

MicroRNA-140-5p inhibits invasion and angiogenesis through targeting VEGF-A in breast cancer

Y Lu, T Qin, J Li, L Wang, Q Zhang, Z Jiang… - Cancer gene therapy, 2017 - nature.com
MicroRNAs (miRNAs) have been proven to be involved in cell metastasis and angiogenesis
by interaction with the target mRNAs. Evidence has been confirmed that miR-140-5p is a …

The role of non-coding RNAs in controlling cell cycle related proteins in cancer cells

S Ghafouri-Fard, H Shoorei, FT Anamag… - Frontiers in …, 2020 - frontiersin.org
Cell cycle is regulated by a number of proteins namely cyclin-dependent kinases (CDKs)
and their associated cyclins which bind with and activate CDKs in a phase specific manner …

Non-coding RNAs as potential therapeutic targets in breast cancer

D Tomar, AS Yadav, D Kumar, G Bhadauriya… - … et Biophysica Acta (BBA …, 2020 - Elsevier
Paradigm shifting studies especially involving non-coding RNAs (ncRNAs) during last few
decades have significantly changed the scientific perspectives regarding the complexity of …

[HTML][HTML] A plant immune protein enables broad antitumor response by rescuing microRNA deficiency

Y Qi, L Ding, S Zhang, S Yao, J Ong, Y Li, H Wu, P Du - Cell, 2022 - cell.com
Cancer cells are featured with uncontrollable activation of cell cycle, and microRNA
deficiency drives tumorigenesis. The RNA-dependent RNA polymerase (RDR) is essential …

Functions and Targets of miR-335 in Cancer

L Ye, F Wang, H Wu, H Yang, Y Yang, Y Ma… - OncoTargets and …, 2021 - Taylor & Francis
MicroRNAs (miRNAs) are small non-coding RNAs (18~ 25 nt in length) that act as master
regulators of eukaryotic gene expression. They might play an oncogenic or …

PARP14 regulates cyclin D1 expression to promote cell-cycle progression

MJ O'Connor, T Thakar, CM Nicolae, GL Moldovan - Oncogene, 2021 - nature.com
Cyclin D1 is an essential regulator of the G1–S cell-cycle transition and is overexpressed in
many cancers. Expression of cyclin D1 is under tight cellular regulation that is controlled by …

The anti-cancer activity and potential clinical application of rice bran extracts and fermentation products

Y Yu, J Zhang, J Wang, B Sun - RSC advances, 2019 - pubs.rsc.org
Rice bran is the main by-product of rice processing and contains approximately 64% of the
nutrients in rice. Its various nutrient elements include rice bran proteins, oil, oryzanol …