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The promising role of miR-21 as a cancer biomarker and its importance in RNA-based therapeutics
D Bautista-Sánchez, C Arriaga-Canon… - … therapy Nucleic acids, 2020 - cell.com
MicroRNAs are small noncoding transcripts that posttranscriptionally regulate gene
expression via base-pairing complementarity. Their role in cancer can be related to tumor …
expression via base-pairing complementarity. Their role in cancer can be related to tumor …
Cell‐to‐cell communication: microRNAs as hormones
Mammalian cells can release different types of extracellular vesicles (EVs), including
exosomes, microvesicles, and apoptotic bodies. Accumulating evidence suggests that EVs …
exosomes, microvesicles, and apoptotic bodies. Accumulating evidence suggests that EVs …
How VEGF-A and its splice variants affect breast cancer development–clinical implications
Background Altered expression levels and structural variations in the vascular endothelial
growth factor (VEGF) have been found to play important roles in cancer development and to …
growth factor (VEGF) have been found to play important roles in cancer development and to …
MicroRNA-140-5p inhibits invasion and angiogenesis through targeting VEGF-A in breast cancer
Y Lu, T Qin, J Li, L Wang, Q Zhang, Z Jiang… - Cancer gene therapy, 2017 - nature.com
MicroRNAs (miRNAs) have been proven to be involved in cell metastasis and angiogenesis
by interaction with the target mRNAs. Evidence has been confirmed that miR-140-5p is a …
by interaction with the target mRNAs. Evidence has been confirmed that miR-140-5p is a …
The role of non-coding RNAs in controlling cell cycle related proteins in cancer cells
Cell cycle is regulated by a number of proteins namely cyclin-dependent kinases (CDKs)
and their associated cyclins which bind with and activate CDKs in a phase specific manner …
and their associated cyclins which bind with and activate CDKs in a phase specific manner …
Non-coding RNAs as potential therapeutic targets in breast cancer
Paradigm shifting studies especially involving non-coding RNAs (ncRNAs) during last few
decades have significantly changed the scientific perspectives regarding the complexity of …
decades have significantly changed the scientific perspectives regarding the complexity of …
[HTML][HTML] A plant immune protein enables broad antitumor response by rescuing microRNA deficiency
Cancer cells are featured with uncontrollable activation of cell cycle, and microRNA
deficiency drives tumorigenesis. The RNA-dependent RNA polymerase (RDR) is essential …
deficiency drives tumorigenesis. The RNA-dependent RNA polymerase (RDR) is essential …
Functions and Targets of miR-335 in Cancer
L Ye, F Wang, H Wu, H Yang, Y Yang, Y Ma… - OncoTargets and …, 2021 - Taylor & Francis
MicroRNAs (miRNAs) are small non-coding RNAs (18~ 25 nt in length) that act as master
regulators of eukaryotic gene expression. They might play an oncogenic or …
regulators of eukaryotic gene expression. They might play an oncogenic or …
PARP14 regulates cyclin D1 expression to promote cell-cycle progression
MJ O'Connor, T Thakar, CM Nicolae, GL Moldovan - Oncogene, 2021 - nature.com
Cyclin D1 is an essential regulator of the G1–S cell-cycle transition and is overexpressed in
many cancers. Expression of cyclin D1 is under tight cellular regulation that is controlled by …
many cancers. Expression of cyclin D1 is under tight cellular regulation that is controlled by …
The anti-cancer activity and potential clinical application of rice bran extracts and fermentation products
Y Yu, J Zhang, J Wang, B Sun - RSC advances, 2019 - pubs.rsc.org
Rice bran is the main by-product of rice processing and contains approximately 64% of the
nutrients in rice. Its various nutrient elements include rice bran proteins, oil, oryzanol …
nutrients in rice. Its various nutrient elements include rice bran proteins, oil, oryzanol …