Amorphous solid dispersions (ASDs) are popular for enhancing the solubility and
bioavailability of poorly water-soluble drugs. Various approaches have been employed to …

Amorphous solid dispersion (ASD) is one of the most effective approaches for delivering
poorly soluble drugs. In ASDs, polymeric materials serve as the carriers in which the drugs …

Poor water solubility of current active pharmaceutical ingredients (APIs) and new chemical
entities (NCEs) is a major hurdle in the development of pharmaceutical dosage forms. More …

The preparation of amorphous solid dispersion (ASD) formulations is a promising strategy to
improve the bioavailability of an active pharmaceutical ingredient (API). By dissolving the …

The purpose of this work is to compare the long-term physical stability of amorphous solid
dispersion (ASD) formulations based on three different commercially used excipients …

To improve the bioavailability of poorly soluble active pharmaceutical ingredients (APIs),
these materials are often integrated into a polymer matrix that acts as a carrier. The resulting …

This study aims to develop amorphous solid dispersion (ASD) of lumefantrine with a cost-
effective approach of spray anti-solvent precipitation. Four acidic polymers …

Lead oxide nanoparticles (PbO NPs) and carboxymethyl cellulose (CMC)/
polyvinylpyrrolidone (PVP) nanocomposite films were prepared by sol‐gel and solution …

The aim of this study was to enhance the kinetic solubility and dissolution rate of ibuprofen
by co-milling with different excipients and to establish the underlying mechanism (s) for such …

Rivaroxaban (RXB) is an orally active direct inhibitor of the activated serine protease Factor
Xa, given as monotherapy in the treatment of venous thromboembolism (VTE). It has been …