Colorimetric sensing for translational applications: from colorants to mechanisms

Z **, W Yim, M Retout, E Housel, W Zhong… - Chemical Society …, 2024 - pubs.rsc.org
Colorimetric sensing offers instant reporting via visible signals. Versus labor-intensive and
instrument-dependent detection methods, colorimetric sensors present advantages …

A comprehensive review on current advances in peptide drug development and design

ACL Lee, JL Harris, KK Khanna, JH Hong - International journal of …, 2019 - mdpi.com
Protein–protein interactions (PPIs) execute many fundamental cellular functions and have
served as prime drug targets over the last two decades. Interfering intracellular PPIs with …

HPEPDOCK: a web server for blind peptide–protein docking based on a hierarchical algorithm

P Zhou, B **, H Li, SY Huang - Nucleic acids research, 2018 - academic.oup.com
Protein–peptide interactions are crucial in many cellular functions. Therefore, determining
the structure of protein–peptide complexes is important for understanding the molecular …

PEP-FOLD3: faster de novo structure prediction for linear peptides in solution and in complex

A Lamiable, P Thévenet, J Rey, M Vavrusa… - Nucleic acids …, 2016 - academic.oup.com
Abstract Structure determination of linear peptides of 5–50 amino acids in aqueous solution
and interacting with proteins is a key aspect in structural biology. PEP-FOLD3 is a novel …

Role of computer-aided drug design in modern drug discovery

SJY Macalino, V Gosu, S Hong, S Choi - Archives of pharmacal research, 2015 - Springer
Drug discovery utilizes chemical biology and computational drug design approaches for the
efficient identification and optimization of lead compounds. Chemical biology is mostly …

GalaxyPepDock: a protein–peptide docking tool based on interaction similarity and energy optimization

H Lee, L Heo, MS Lee, C Seok - Nucleic acids research, 2015 - academic.oup.com
Protein–peptide interactions are involved in a wide range of biological processes and are
attractive targets for therapeutic purposes because of their small interfaces. Therefore …

Benchmarking of different molecular docking methods for protein-peptide docking

P Agrawal, H Singh, HK Srivastava, S Singh… - BMC …, 2019 - Springer
Background Molecular docking studies on protein-peptide interactions are a challenging
and time-consuming task because peptides are generally more flexible than proteins and …

[HTML][HTML] Protein–peptide docking: opportunities and challenges

M Ciemny, M Kurcinski, K Kamel, A Kolinski, N Alam… - Drug discovery today, 2018 - Elsevier
Highlights•We provide an overview of protein-peptide docking methods and their
applications.•Peptide docking tools can be divided on template-based, local and global …

The eukaryotic linear motif resource ELM: 10 years and counting

H Dinkel, K Van Roey, S Michael… - Nucleic acids …, 2014 - academic.oup.com
The eukaryotic linear motif (ELM http://elm. eu. org) resource is a hub for collecting,
classifying and curating information about short linear motifs (SLiMs). For> 10 years, this …

Simulated gastrointestinal digestion of camel and bovine casein hydrolysates: Identification and characterization of novel anti-diabetic bioactive peptides

P Mudgil, H Kamal, BP Kilari, MASM Salim, CY Gan… - Food chemistry, 2021 - Elsevier
Camel milk proteins are an important substrate for bioactive peptides generation. This study
investigates in-vitro antidiabetic effect (via inhibition of α-amylase (AA), α-glucosidase (AG) …