Arynes are among the most active organic intermediates and have found numerous
applications in expeditious preparation of substituted arenes. In the past 20 years, chemists …

Recent advances in understanding different RNAs and unique features of their biology have
revealed a wealth of information. However, approaches to identify small molecules that …

Molecular cages are sought after as receptors and catalysts. However, typical dynamic
covalent chemistry approaches restrict the shape‐persistence, solubility and stability of self …

Triptycenes are an intriguing class of organic molecules with several unusual
characteristics, such as a propeller‐like shape, saddle‐like cavities around a symmetrical …

We report on the design and synthesis of triptycene–peptide hybrids (TPHs), 5, syn-6, and
anti-6, which are conjugates of a triptycene core unit with two or three cationic KKKGG …

Arynes are important and versatile intermediates in a variety of transformations. Commonly
used solvents for aryne chemistry include acetonitrile and dichloromethane. Although rarely …

Non-canonical DNA structures, particularly 3-Way Junctions (3WJs) that are transiently
formed during DNA replication, have recently emerged as promising chemotherapeutic …

Regulation of the heat shock response (HSR) is essential in all living systems. In E. coli, the
HSR is regulated by an alternative σ factor, σ32, which is encoded by the rpoH gene. The …

Herein, we show that bridgehead-functionalized triptycene quinones can be rapidly and
conveniently prepared in good to high yields by Lewis acid–catalyzed cycloaddition of 1, 4 …

Recently, the utility of triptycene as a scaffold for targeting nucleic acid three-way junctions
was demonstrated. A rapid, efficient route for the synthesis of bridgehead-substituted …