BREATHING: Rhythmicity, Plasticity, Chemosensitivity

JL Feldman, GS Mitchell… - Annual review of …, 2003 - annualreviews.org
▪ Abstract Breathing is a vital behavior that is particularly amenable to experimental
investigation. We review recent progress on three problems of broad interest.(i) Where and …

The ventilatory response to hypoxia in mammals: mechanisms, measurement, and analysis

LJ Teppema, A Dahan - Physiological reviews, 2010 - journals.physiology.org
The respiratory response to hypoxia in mammals develops from an inhibition of breathing
movements in utero into a sustained increase in ventilation in the adult. This ventilatory …

[HTML][HTML] Respiratory sinus arrhythmia (RSA), vagal tone and biobehavioral integration: Beyond parasympathetic function

P Grossman - Biological Psychology, 2024 - Elsevier
Linchpin to the entire area of psychophysiological research and discussion of the vagus is
the respiratory and cardiovascular phenomenon known as respiratory sinus arrhythmia …

[HTML][HTML] Fundamental challenges and likely refutations of the five basic premises of the polyvagal theory

P Grossman - Biological Psychology, 2023 - Elsevier
The polyvagal collection of hypotheses is based upon five essential premises, as stated by
its author (Porges, 2011). Polyvagal conjectures rest on a primary assumption that brainstem …

Domoic acid and human exposure risks: a review

KA Lefebvre, A Robertson - Toxicon, 2010 - Elsevier
Domoic acid is a potent neurotoxin that is naturally produced by several diatom species of
the genus Pseudo-nitzschia. The toxin acts as a glutamate agonist and is excitotoxic in the …

Whither vagal tone

GG Berntson, JT Cacioppo, P Grossman - Biological psychology, 2007 - Elsevier
Measures of respiratory sinus arrhythmia (RSA) have been widely applied in the
physiological and psychophysiological literature as an index of vagal control of the heart …

Respiratory neuroplasticity: Mechanisms and translational implications of phrenic motor plasticity

GS Mitchell, TL Baker - Handbook of Clinical Neurology, 2022 - Elsevier
Widespread appreciation that neuroplasticity is an essential feature of the neural system
controlling breathing has emerged only in recent years. In this chapter, we focus on …

Activation of an efferent cholinergic pathway produces strong protection against myocardial ischemia/reperfusion injury in rats

C Mioni, C Bazzani, D Giuliani, D Altavilla… - Critical care …, 2005 - journals.lww.com
Objective: A vagus nerve–mediated, brain cholinergic protective mechanism activated by
melanocortin peptides is operative in conditions of circulatory shock; moreover, there is …

Chronic intermittent hypoxia impairs baroreflex control of heart rate but enhances heart rate responses to vagal efferent stimulation in anesthetized mice

M Lin, R Liu, D Gozal, WB Wead… - American Journal …, 2007 - journals.physiology.org
Chronic intermittent hypoxia (CIH) leads to increased sympathetic nerve activity and arterial
hypertension. In this study, we tested the hypothesis that CIH impairs baroreflex (BR) control …

A size selective vascular barrier in the rat area postrema formed by perivascular macrophages and the extracellular matrix

CL Willis, CJ Garwood, DE Ray - Neuroscience, 2007 - Elsevier
The fenestrated microvasculature of the area postrema shows a less restrictive blood–brain
barrier than is found in other areas of the CNS. We have studied the expression and …