Organs-on-chips: into the next decade
LA Low, C Mummery, BR Berridge, CP Austin… - Nature Reviews Drug …, 2021 - nature.com
Abstract Organs-on-chips (OoCs), also known as microphysiological systems or 'tissue
chips'(the terms are synonymous), have attracted substantial interest in recent years owing …
chips'(the terms are synonymous), have attracted substantial interest in recent years owing …
Nip the bubble in the bud: a guide to avoid gas nucleation in microfluidics
Gas bubbles are almost a routine occurrence encountered by researchers working in the
field of microfluidics. The spontaneous and unexpected nature of gas bubbles represents a …
field of microfluidics. The spontaneous and unexpected nature of gas bubbles represents a …
Flow-induced stress on adherent cells in microfluidic devices
Transduction of mechanical forces and chemical signals affect every cell in the human body.
Fluid flow in systems such as the lymphatic or circulatory systems modulates not only cell …
Fluid flow in systems such as the lymphatic or circulatory systems modulates not only cell …
Microfluidics for understanding model organisms
New microfluidic systems for whole organism analysis and experimentation are catalyzing
biological breakthroughs across many fields, from human health to fundamental biology …
biological breakthroughs across many fields, from human health to fundamental biology …
Artificial intelligence-controlled microfluidic device for fluid automation and bubble removal of immunoassay operated by a smartphone
There have been tremendous innovations in microfluidic clinical diagnostics to facilitate
novel point-of-care testing (POCT) over the past decades. However, the automatic operation …
novel point-of-care testing (POCT) over the past decades. However, the automatic operation …
Microfluidics with fluid walls
Microfluidics has great potential, but the complexity of fabricating and operating devices has
limited its use. Here we describe a method—Freestyle Fluidics—that overcomes many key …
limited its use. Here we describe a method—Freestyle Fluidics—that overcomes many key …
Recent progress in fabricating superaerophobic and superaerophilic surfaces
In spite of large amount of research in fabricating surfaces of varying wettability by
biomimicking the naturally occurring surfaces, the work on fundamentally and industrially …
biomimicking the naturally occurring surfaces, the work on fundamentally and industrially …
Continuous in-flight synthesis for on-demand delivery of ligand-free colloidal gold nanoparticles
We demonstrate an entirely new method of nanoparticle chemical synthesis based on liquid
droplet irradiation with ultralow (< 0.1 eV) energy electrons. While nanoparticle formation via …
droplet irradiation with ultralow (< 0.1 eV) energy electrons. While nanoparticle formation via …
High-efficiency inertial separation of microparticles using elevated columned reservoirs and vortex technique for lab-on-a-chip applications
The discovery of circulating tumor cells (CTCs) has envisioned an excellent outlook for
cancer diagnosis and prognosis. Among numerous efforts proposed for CTCs isolation …
cancer diagnosis and prognosis. Among numerous efforts proposed for CTCs isolation …
Vacuum-driven power-free microfluidics utilizing the gas solubility or permeability of polydimethylsiloxane (PDMS)
Suitable pum** methods for flow control remain a major technical hurdle in the path of
biomedical microfluidic systems for point-of-care (POC) diagnostics. A vacuum-driven power …
biomedical microfluidic systems for point-of-care (POC) diagnostics. A vacuum-driven power …