Chemotherapy side-effects: not all DNA damage is equal

WMC van den Boogaard, DSJ Komninos, WP Vermeij - Cancers, 2022 - mdpi.com
Simple Summary The number of children and adults with cancer that are completely cured is
still increasing thanks to effective anti-cancer therapy, but they may be confronted with the …

Chemotherapy-induced peripheral neuropathy: epidemiology, pathomechanisms and treatment

J Burgess, M Ferdousi, D Gosal, C Boon… - Oncology and …, 2021 - Springer
Purpose This review provides an update on the current clinical, epidemiological and
pathophysiological evidence alongside the diagnostic, prevention and treatment approach …

Prevention and management of chemotherapy-induced peripheral neuropathy in survivors of adult cancers: American Society of Clinical Oncology clinical practice …

DL Hershman, C Lacchetti, RH Dworkin… - Journal of clinical …, 2014 - ascopubs.org
Purpose To provide evidence-based guidance on the optimum prevention and treatment
approaches in the management of chemotherapy-induced peripheral neuropathies (CIPN) …

American Cancer Society colorectal cancer survivorship care guidelines

K El‐Shami, KC Oeffinger, NL Erb… - CA: a cancer journal …, 2015 - Wiley Online Library
Answer questions and earn CME/CNE Colorectal cancer (CRC) is the third most common
cancer and third leading cause of cancer death in both men and women and second leading …

Neuroinflammatory process involved in different preclinical models of chemotherapy-induced peripheral neuropathy

G Fumagalli, L Monza, G Cavaletti, R Rigolio… - Frontiers in …, 2021 - frontiersin.org
Peripheral neuropathies are characterized by nerves damage and axonal loss, and they
could be classified in hereditary or acquired forms. Acquired peripheral neuropathies are …

Effect of duloxetine on pain, function, and quality of life among patients with chemotherapy-induced painful peripheral neuropathy: a randomized clinical trial

EML Smith, H Pang, C Cirrincione, S Fleishman… - Jama, 2013 - jamanetwork.com
Importance There are no known effective treatments for painful chemotherapy-induced
peripheral neuropathy. Objective To determine the effect of duloxetine, 60 mg daily, on …

Long-term effects, pathophysiological mechanisms, and risk factors of chemotherapy-induced peripheral neuropathies: a comprehensive literature review

N Kerckhove, A Collin, S Condé, C Chaleteix… - Frontiers in …, 2017 - frontiersin.org
Neurotoxic anticancer drugs, such as platinum-based anticancer drugs, taxanes, vinca
alkaloids, and proteasome/angiogenesis inhibitors are responsible for chemotherapy …

[HTML][HTML] Oxidative stress and nerve damage: role in chemotherapy induced peripheral neuropathy

A Areti, VG Yerra, VGM Naidu, A Kumar - Redox biology, 2014 - Elsevier
Peripheral neuropathy is a severe dose limiting toxicity associated with cancer
chemotherapy. Ever since it was identified, the clear pathological mechanisms underlying …

Mechanism-based treatment for chemotherapy-induced peripheral neuropathic pain

M Sisignano, R Baron, K Scholich… - Nature Reviews …, 2014 - nature.com
Chemotherapy-induced peripheral neuropathic pain (CIPNP)—a severe adverse effect
observed in up to 80% of patients during treatment with antineoplastic drugs—limits the …

[HTML][HTML] Overview of cisplatin-induced neurotoxicity and ototoxicity, and the protective agents

NAG Dos Santos, RS Ferreira… - Food and chemical …, 2020 - Elsevier
Cisplatin has dramatically improved the survival rate of cancer patients, but it has also
increased the prevalence of hearing and neurological deficits in this population. Cisplatin …