The blood–brain barrier (BBB) restricts the transport of potential therapeutic moieties to the
brain. Direct targeting the brain via olfactory and trigeminal neural pathways by passing the …

Despite significant advances in research, the prognosis for both primary and secondary
brain cancers remains poor. The blood-brain barrier (BBB) is a complex and unique semi …

The photothermal response of plasmonic nanomaterials can be exploited for a number of
biomedical applications in diagnostics (biosensing and optoacoustic imaging) and therapy …

MicroRNAs are critical regulators of cancer initiation, progression, and dissemination.
Extensive evidence suggests that the inhibition of over-expressed oncogenic miRNA …

Graphene oxide (GO) has attracted tremendous attention as a most promising nanomaterial
among the carbon family since it emerged as a polynomial functional tool with rational …

Hyperthermia therapy (HT) of cancer is a well-known treatment approach. With the advent of
new technologies, HT approaches are now important for the treatment of brain tumors. We …

Traditional anti-cancer treatments are inefficient against glioblastoma, which remains one of
the deadliest and most aggressive cancers. Nano-drugs could help to improve this situation …

Gold nanoparticles (AuNPs) have arisen a lot of interest in the clinical realms of
nanomedicine. Despite the large advances made in cancer research using AuNPs, their use …

Temozolomide (TMZ) is a standard-of-care chemotherapeutic drug for the treatment of
glioblastoma (GBM), but TMZ-acquired resistance limits its therapeutic effect. In this study …

Glioblastoma multiform (GBM) is the most common brain tumor. The current GBM treatments
comprise of radiation therapy, chemotherapy and surgery. One of the most important …