Smart drug delivery systems (DDSs) have attracted the attention of many scientists, as
carriers that can be stimulated by changes in environmental parameters such as …

Due to the potential use as transfecting agents of nucleic acids (DNA or RNA), multivalent
cationic non-viral vectors have received special attention in the last decade. Much effort has …

Aqueous solutions of polyelectrolytes are known to be complex; however, when the charged
polymer carries a simple counterion such as sodium or chloride it is usually soluble in water …

Mendelian genetics spark the century‐old revolution in genetic engineering. DNA structural
engineering may well spark a similar revolution in chemistry. The first few man‐made DNA …

Poly (N‐isopropylacrylamide)(PNIPAM) is a versatile polymer known for its phase transition
properties, exhibiting a lower critical solution temperature (LCST) of approximately 32° C …

Liposomes composed of egg phosphatidylcholine and cholesterol were modified with the
temperature-responsive polymer poly (N-isopropylacrylamide-co-N, N …

Ribonucleic acid (RNA) drugs have shown promising therapeutic effects for various
diseases in clinical and preclinical studies, owing to their capability to regulate the …

The study presents the synthesis of original cholesterol-terminated copolymers comprising
acetylacetone-based (AcacI) and N-isopropylacrylamide (NIPAAm) units with a varied …

Drug delivery by nanoparticle carriers has been limited by inefficient intracellular drug
delivery. Temperature-responsive poly (N-isopropylacrylamide)(PNIPAAm)-modified …

Short interfering RNA (siRNA) delivery systems using nanoparticle carriers have been
limited by inefficient intracellular delivery. One drawback is the poor cellular uptake of …