Obesity is a chronic, progressive and relapsing disease with a rising global prevalence
associated with increased morbidity and mortality and reduced quality of life. Treatment of …

Recent insights into the pathophysiologic underlying mechanisms of obesity have led to the
discovery of several promising drug targets and novel therapeutic strategies to address the …

Background Obesity poses significant challenges to healthcare globally, particularly through
its bi‐directional relationship with co‐morbid metabolic conditions such as type 2 diabetes …

Conditions and comorbidities of obesity mirror those of ageing and age‐related diseases.
Obesity and ageing share a similar spectrum of phenotypes such as compromised genomic …

Obesity is a global pandemic that has been associated with the development of breast,
endometrial, large intestine, renal, esophageal, and pancreatic cancer. Obesity is also …

This review analyzes the published evidence regarding maternal factors that influence the
developmental programming of long-term adiposity in humans and animals via the central …

Obesity is increasing in prevalence across all age groups. Long-term obesity can lead to the
development of metabolic and cardiovascular diseases through its effects on adipose …

Background and significance Obesity is a chronic disease, warranting long-term medical
intervention. We evaluated effects of testosterone (T) therapy (Th) in men with T deficiency …

Being overweight or obese can predispose people to chronic diseases and metabolic
disorders such as cardiovascular illnesses, diabetes, Alzheimer's disease, and cancer …

Background Total knee arthroplasty is known to successfully alleviate pain and improve
function in endstage knee osteoarthritis. However, there is some controversy with regard to …