Effects of allopurinol on the progression of chronic kidney disease

SV Badve, EM Pascoe, A Tiku… - … England Journal of …, 2020 - Mass Medical Soc
Background Elevated serum urate levels are associated with progression of chronic kidney
disease. Whether urate-lowering treatment with allopurinol can attenuate the decline of the …

Excess comorbidities in gout: the causal paradigm and pleiotropic approaches to care

HK Choi, N McCormick, C Yokose - Nature Reviews Rheumatology, 2022 - nature.com
Gout is a common hyperuricaemic metabolic condition that leads to painful inflammatory
arthritis and a high comorbidity burden, especially cardiometabolic-renal (CMR) conditions …

KDIGO 2024 clinical practice guideline for the evaluation and management of chronic kidney disease

PE Stevens, SB Ahmed, JJ Carrero… - Kidney …, 2024 - kidney-international.org
This article is published as part of a supplement sponsored by Kidney Disease: Improving
Global Outcomes (KDIGO). The opinions or views expressed in this supplement are those of …

Comparative Effectiveness of Sodium–Glucose Cotransporter-2 Inhibitors for Recurrent Gout Flares and Gout-Primary Emergency Department Visits and …

N McCormick, C Yokose, J Wei, N Lu… - Annals of Internal …, 2023 - acpjournals.org
Background: Sodium–glucose cotransporter-2 inhibitors (SGLT2is) decrease serum urate
levels, but whether this translates into prevention of recurrent flares among patients with …

[HTML][HTML] Uric acid and chronic kidney disease: still more to do

RJ Johnson, LGS Lozada, MA Lanaspa, F Piani… - Kidney International …, 2023 - Elsevier
Gout and hyperuricemia are present in 25% and 60% of patients with chronic kidney
disease (CKD), respectively. Despite the common association, the role of uric acid in the …

Molecular mechanisms in early diabetic kidney disease: glomerular endothelial cell dysfunction

E Lassén, IS Daehn - International journal of molecular sciences, 2020 - mdpi.com
Diabetic kidney disease (DKD) is the leading cause of end-stage renal disease (ESRD), with
prevalence increasing at an alarming rate worldwide and today, there are no known cures …