COVID-19 in pregnancy: implications for fetal brain development

LL Shook, EL Sullivan, JO Lo, RH Perlis… - Trends in molecular …, 2022 - cell.com
The impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection
during pregnancy on the develo** fetal brain is poorly understood. Other antenatal …

Hallucinogens and Serotonin 5-HT2A Receptor-Mediated Signaling Pathways

JF López-Giménez, J González-Maeso - Behavioral neurobiology of …, 2018 - Springer
The neuropsychological effects of naturally occurring psychoactive chemicals have been
recognized for millennia. Hallucinogens, which include naturally occurring chemicals such …

Advanced functional nanomaterials for theranostics

H Huang, JF Lovell - Advanced functional materials, 2017 - Wiley Online Library
Nanoscale materials have been explored extensively as agents for therapeutic and
diagnostic (ie, theranostic) applications. Research efforts have shifted from exploring new …

Maternal immune activation in neurodevelopmental disorders

CM Solek, N Farooqi, M Verly, TK Lim… - Developmental …, 2018 - Wiley Online Library
Converging lines of evidence from basic science and clinical studies suggest a relationship
between maternal immune activation (MIA) and neurodevelopmental disorders such as …

The role of maternal immune activation in altering the neurodevelopmental trajectories of offspring: A translational review of neuroimaging studies with implications for …

E Guma, E Plitman, MM Chakravarty - Neuroscience & Biobehavioral …, 2019 - Elsevier
Exposure to maternal infection in utero increases the risk that offspring will develop
neurodevelopmental disorders such as autism spectrum disorder (ASD) and schizophrenia …

Metal transporter Zip14 (Slc39a14) deletion in mice increases manganese deposition and produces neurotoxic signatures and diminished motor activity

TB Aydemir, MH Kim, J Kim, LM Colon-Perez… - Journal of …, 2017 - jneurosci.org
Mutations in human ZIP14 have been linked to symptoms of the early onset of Parkinsonism
and Dystonia. This phenotype is likely related to excess manganese accumulation in the …

Chronic cannabis promotes pro-hallucinogenic signaling of 5-HT2A receptors through Akt/mTOR pathway

I Ibarra-Lecue, I Mollinedo-Gajate, JJ Meana… - …, 2018 - nature.com
Long-term use of potent cannabis during adolescence increases the risk of develo**
schizophrenia later in life, but to date, the mechanisms involved remain unknown. Several …

Paliperidone reverts Toll-like receptor 3 signaling pathway activation and cognitive deficits in a maternal immune activation mouse model of schizophrenia

KS MacDowell, E Munarriz-Cuezva, JR Caso… - …, 2017 - Elsevier
The pathophysiology of psychotic disorders is multifactorial, including alterations in the
immune system caused by exogenous or endogenous factors. Epidemiological and …

Lasting dynamic effects of the psychedelic 2, 5-dimethoxy-4-iodoamphetamine ((±)-DOI) on cognitive flexibility

M Šabanović, A Lazari, M Blanco-Pozo, C Tisca… - Molecular …, 2024 - nature.com
Psychedelic drugs can aid fast and lasting remission from various neuropsychiatric
disorders, though the underlying mechanisms remain unclear. Preclinical studies suggest …

Fully automated head-twitch detection system for the study of 5-HT2A receptor pharmacology in vivo

M de la Fuente Revenga, JM Shin, HZ Vohra… - Scientific reports, 2019 - nature.com
Head-twitch behavior (HTR) is the behavioral signature of psychedelic drugs upon
stimulation of the serotonin 5-HT2A receptor (5-HT2AR) in rodents. Following the previous …