Guest back-folding: a molecular design strategy that produces a deep-red fluorescent host/guest pair with picomolar affinity in water

W Liu, A Johnson, BD Smith - Journal of the American Chemical …, 2018 - ACS Publications
One of the major goals of modern supramolecular chemistry, with important practical
relevance in many technical fields, is the development of synthetic host/guest partners with …

Conjugated bis (enaminones) as effective templates for rotaxane assembly and their post-synthetic modifications

SS Razi, M Marin-Luna, M Alajarin… - Communications …, 2024 - nature.com
The development of efficient methods for the synthesis of mechanically interlocked
compounds is currently considered a major challenge in supramolecular chemistry. Twofold …

Mechanically Planar-to-Point Chirality Transmission in [2] Rotaxanes

J Puigcerver, M Marin-Luna… - Journal of the …, 2024 - ACS Publications
Herein we describe an effective transmission of chirality, from mechanically planar chirality
to point chirality, in hydrogen-bonded [2] rotaxanes. A highly selective mono-N-methylation …

The rotational movement in solution of fumaramide-vs. succinamide [2] rotaxanes: The influence of intercomponent interactions

FFS Farias, GH Weimer, SK Kunz, PRS Salbego… - Journal of Molecular …, 2023 - Elsevier
Due to their intrinsic topological features, most artificial molecular devices are based on
rotaxane molecules. One of the most important characteristics of this class of compounds is …

Crystallization Mechanisms Applied to Understand the Crystal Formation of Rotaxanes

T Orlando, PRS Salbego, FFS Farias… - European Journal of …, 2019 - Wiley Online Library
The present study discusses the crystalline packing formation of several [2] rotaxanes with
Leigh‐type tetralactam macrocycle bearing different threads. The presence of solvent …

Polymorphism in a Rotaxane Molecule: Intra-and Intermolecular Understanding

T Orlando, PRS Salbego, CLR Taschetto… - Crystal Growth & …, 2018 - ACS Publications
Polymorphs have been widely studied since different crystalline phases of the same
compound may have distinct properties. Macromolecules are an area of major study with …

Supramolecular Packing of a Series of N-Phenylamides and the Role of NH···O═C Interactions

AB Pagliari, T Orlando, PRS Salbego, GC Zimmer… - ACS …, 2018 - ACS Publications
A series of seven N-phenylamides [R–C (O) NHPh, in which R: CH3, C (CH3) 3, Ph, CF3,
CCl3, CBr3, and H] were used as models in this study. Molecular packing and …

Stereocontrol in the Synthesis of β-lactams arising from the Interlocked Structure of Benzylfumaramide-based Hydrogen-bonded [2] Rotaxanes

A Martinez-Cuezva, C Lopez-Leonardo, M Alajarin… - Synlett, 2019 - thieme-connect.com
β-Lactams are highly valuable compounds due to their antibiotic activity. Among the number
of well-established methodologies for building this privileged scaffold, our research group …

High affinity threading of a new tetralactam macrocycle in water by fluorescent deep-red and near-infrared squaraine dyes

JM Dempsey, C Zhai, HH McGarraugh… - Chemical …, 2019 - pubs.rsc.org
A new tetralactam macrocycle was prepared and found to encapsulate deep-red and near-
infrared squaraine and croconaine dyes in water with tunable threading kinetics. The new …

[2] Rotaxane Solvates: Insights into the Presence of Solvents in the Crystal Lattice

FFS Farias, GH Weimer, SK Kunz… - Crystal Growth & …, 2024 - ACS Publications
During synthesis and purification, compounds are exposed to various solvents. These
solvents can, at times, assemble in the solid state. This association can arise from …