Current scenario of quinolone hybrids with potential antibacterial activity against ESKAPE pathogens

J Gao, H Hou, F Gao - European Journal of Medicinal Chemistry, 2023 - Elsevier
Abstract The ESKAPE (Escherichia coli/E. coli, Staphylococcus aureus/S. aureus, Klebsiella
pneumonia/K. pneumoniae, Acinetobacter Baumannii/A. baumannii, Pseudomonas …

The antibacterial activity of fluoroquinolone derivatives: An update (2018–2021)

Y Jia, L Zhao - European journal of medicinal chemistry, 2021 - Elsevier
Bacterial infection is amongst the most common diseases in community and hospital
settings. Fluoroquinolones, exerting the antibacterial activity through binding to type II …

New potent ciprofloxacin-uracil conjugates as DNA gyrase and topoisomerase IV inhibitors against methicillin-resistant Staphylococcus aureus

M Samir, M Ramadan, MH Abdelrahman… - Bioorganic & Medicinal …, 2022 - Elsevier
A series of ciprofloxacin-uracil conjugates 5a-t were synthesized and identified by 1 H NMR,
13 C NMR, mass spectroscopy and elemental analyses. The antibacterial results revealed …

2D polymeric lanthanide (III) compounds based on novel bright green emitting enaminone ligand

KS Smirnova, EA Ivanova, IP Pozdnyakov… - Inorganica Chimica …, 2022 - Elsevier
Abstract New enaminone derivative, 2-{[(4-methoxyphenyl) amino] methylene}-5, 5-dimethyl-
cyclohexane-1, 3-dione (HL), and lanthanide (III) compounds based on it [Ln (HL) 2 (NO 3) …

Theoretical insight of ciprofloxacin removal from water using boron nitride (B12N12) nanocage

Q Ali, AA Khan, M Yar, M Khan, R Ahmad… - Surfaces and Interfaces, 2022 - Elsevier
In the present study we used B 12 N 12 nanocage for the removal of ciprofloxacin (CIP) from
water using DFT approach. Three positions of CIP are considered for the interaction with B …

Exploring the interaction of biologically active compounds with DNA through the application of the SwitchSense technique, UV–Vis spectroscopy, and computational …

A Ciesielska, J Brzeski, D Zarzeczańska… - … Acta Part A: Molecular …, 2024 - Elsevier
DNA is a key target for anticancer and antimicrobial drugs. Assessing the bioactivity of
compounds involves in silico and instrumental studies to determine their affinity for …

Cyanomethylquinolones as a New Class of Potential Multitargeting Broad-Spectrum Antibacterial Agents

YM Tan, J Zhang, YJ Wei, YG Hu, SR Li… - Journal of Medicinal …, 2024 - ACS Publications
This work identified a class of cyanomethylquinolones (CQs) and their carboxyl analogues
as potential multitargeting antibacterial candidates. Most of the prepared compounds …

Polymeric REE coordination compounds based on novel enaminone derivative

KS Smirnova, EA Ivanova, IV Eltsov, IP Pozdnyakov… - Polyhedron, 2022 - Elsevier
Abstract A novel enaminone derivative, 2-{[(3-methoxyphenyl) amino] methylene}-5, 5-
dimethylcyclohexane-1, 3-dione (HL) and its lanthanide (III) complexes [Ln (HL) 2 (NO 3) 3] …

Assessment of the potential and application of Be12O12 nanocage for removal of ciprofloxacin from water employing density functional theory

Q Ali, A Shakoor, G Rehman, M Ur Rehman, M Khan… - Scientific Reports, 2025 - nature.com
The modern world is facing the issue of emerging pollutants for its sustainable development.
We report a detailed study on the abatement of ciprofloxacin (CIP) by Be12O12 nanocage …

Advancements in Synthetic Strategies and Biological Effects of Ciprofloxacin Derivatives: A Review

V Khwaza, S Mlala, BA Aderibigbe - International Journal of Molecular …, 2024 - mdpi.com
Ciprofloxacin is a widely used antibiotic in the fluoroquinolone class. It is widely
acknowledged by various researchers worldwide, and it has been documented to have a …