The historical development of discoveries and conceptual frames for understanding the
hemorrhagic activity induced by viperid snake venoms and by hemorrhagic …

Zinc-dependent metalloproteinases are responsible for the hemorrhagic activity
characteristic of viperid snake venoms. Snake venom metalloproteinases (SVMPs) are …

The Handbook of Venoms and Toxins of Reptiles offers" one-stop shop**" to all biologists,
biochemists, toxicologists, physicians, clinicians, and epidemiologists, and informed …

Hemorrhage is one of the most significant effects in envenomings induced by viperid
snakebites. Damage to the microvasculature, induced by snake venom metalloproteinases …

Snake venoms contain a number of serine and metalloproteinases and included among
these are the fibrin (ogen) olytic proteinases. Some years ago it was postulated that the fibrin …

Gene duplication is a key mechanism for the adaptive evolution and neofunctionalization of
gene families. Large multigene families often exhibit complex evolutionary histories as a …

Snake venom metalloproteinases (SVMPs) affect the extracellular matrix (ECM) in multiple
and complex ways. Previously, the combination of various methodological platforms …

Aqueous extract from Casearia sylvestris leaves, a typical plant from Brazilian open
pastures, was able to neutralize the hemorrhagic activity caused by Bothrops asper …

The human body has a set of physiological processes, known as hemostasis, which keeps
the blood fluid and free of clots in normal vessels; in the case of vascular injury, this process …

Abstract Phospholipase A2 (PLA2) is the main constituent of snake venom. PLA2 enzymes
catalyze the Ca 2+ dependent hydrolysis of 2-acyl ester bonds of 3-sn-phospholipids …