Protein phosphatase 2A (PP 2A) is a serine/threonine phosphatase involved in the
regulation of many cellular processes. A confirmed tumor suppressor protein, PP 2A is …

Oral chemotherapy is an important topic in the 21st century medicine, which may radically
change the current regimen of chemotherapy and greatly improve the quality of life of the …

Chemotherapy has been used for cancer treatment already for almost 70 years by targeting
the proliferation potential and metastasising ability of tumour cells. Despite the progress …

Redox dysregulation originating from metabolic alterations and dependence on mitogenic
and survival signaling through reactive oxygen species represents a specific vulnerability of …

Over the last few decades, many different groups have been engaged in studies of new
roles for mitochondria, particularly the coupling of alterations in the redox pathway with the …

We report a strategy to make use of poly (lactic-co-glycolic acid) nanoparticle (PLGA NPs)
for co-delivery of docetaxel (DTX) as a model anticancer drug together with vitamin E TPGS …

Current observations in the literature suggest that vitamin E may be a suitable candidate for
the adjuvant treatment of cancer. Even though historically most research focused on α …

Abstract α-Tocopheryl succinate (α-TOS) is a selective inducer of apoptosis in cancer cells,
which involves the accumulation of reactive oxygen species (ROS). The molecular target of …

During the last 90 years since the discovery of vitamin E, research has focused on different
properties of this molecule, the focus often depending on the specific techniques and …

In this study, two types of the fluoroamphiphile analogs were synthesized and self-
assembled into the “core–shell” micellar nanocarriers for intracellular delivery and organelle …