Hypothalamic control of innate social behaviors

L Mei, T Osakada, D Lin - Science, 2023 - science.org
Sexual, parental, and aggressive behaviors are central to the reproductive success of
individuals and species survival and thus are supported by hardwired neural circuits. The …

The structural and functional complexity of the integrative hypothalamus

H Fong, J Zheng, D Kurrasch - Science, 2023 - science.org
The hypothalamus (“hypo” meaning below, and “thalamus” meaning bed) consists of
regulatory circuits that support basic life functions that ensure survival. Sitting at the interface …

A GnRH neuronal population in the olfactory bulb translates socially relevant odors into reproductive behavior in male mice

L Decoster, S Trova, S Zucca, J Bulk, A Gouveia… - Nature …, 2024 - nature.com
Hypothalamic gonadotropin-releasing hormone (GnRH) neurons regulate fertility and
integrate hormonal status with environmental cues to ensure reproductive success. Here we …

Sexually dimorphic dopaminergic circuits determine sex preference

A Wei, A Zhao, C Zheng, N Dong, X Cheng, X Duan… - Science, 2025 - science.org
Sociosexual preference is critical for reproduction and survival. However, neural
mechanisms encoding social decisions on sex preference remain unclear. In this study, we …

Neurobiology of Social Interactions Across Species Role of neuroestrogens in the regulation of social behaviors–From social recognition to mating

D Aspesi, CA Cornil - Neuroscience & Biobehavioral Reviews, 2024 - Elsevier
In this mini-review, we summarize the brain distribution of aromatase, the enzyme catalyzing
the synthesis of estrogens from androgens, and the mechanisms responsible for regulating …

Mating proximity blinds threat perception

L Cazalé-Debat, L Scheunemann, M Day… - Nature, 2024 - nature.com
Romantic engagement can bias sensory perception. This 'love blindness' reflects a common
behavioural principle across organisms: favouring pursuit of a coveted reward over potential …

Excitation-inhibition imbalance in medial preoptic area circuits underlies chronic stress-induced depression-like states

C Tao, GW Zhang, WJ Sun, JJ Huang, LI Zhang… - Nature …, 2024 - nature.com
Dysregulation of brain homeostasis is associated with neuropsychiatric conditions such as
major depressive disorder. However, underlying neural-circuit mechanisms remain not well …

[HTML][HTML] Auditory entrainment coordinates cortical-BNST-NAc triple time locking to alleviate the depressive disorder

X Lv, Y Wang, Y Zhang, S Ma, J Liu, K Ye, Y Wu… - Cell Reports, 2024 - cell.com
Listening to music is a promising and accessible intervention for alleviating symptoms of
major depressive disorder. However, the neural mechanisms underlying its antidepressant …

Engineering, applications, and future perspectives of GPCR‐based genetically encoded fluorescent indicators for neuromodulators

VL Rohner, PJ Lamothe‐Molina… - Journal of …, 2024 - Wiley Online Library
This review explores the evolving landscape of G‐protein‐coupled receptor (GPCR)‐based
genetically encoded fluorescent indicators (GEFIs), with a focus on their development …

Reproductive function and behaviors: an update on the role of neural estrogen receptors alpha and beta

T Torres, N Adam, S Mhaouty-Kodja… - Frontiers in …, 2024 - frontiersin.org
Infertility is becoming a major public health problem, with increasing frequency due to
medical, environmental and societal causes. The increasingly late age of childbearing …