Cell types are the basic functional units of an organism. Cell types exhibit diverse
phenotypic properties at multiple levels, making them challenging to define, categorize, and …

The prefrontal cortex (PFC) orchestrates higher brain function and becomes disrupted in
many mental health disorders. The rodent medial PFC (mPFC) possesses an enormous …

A mammalian brain is composed of numerous cell types organized in an intricate manner to
form functional neural circuits. Single-cell RNA sequencing allows systematic identification …

Dendritic and axonal morphology reflects the input and output of neurons and is a defining
feature of neuronal types,, yet our knowledge of its diversity remains limited. Here, to …

The neocortex is disproportionately expanded in human compared with mouse,, both in its
total volume relative to subcortical structures and in the proportion occupied by …

The anatomy of the mammalian visual system, from the retina to the neocortex, is organized
hierarchically. However, direct observation of cellular-level functional interactions across this …

Prefrontal cortex (PFC) is the cognitive center that integrates and regulates global brain
activity. However, the whole-brain organization of PFC axon projections remains poorly …

Recent large-scale collaborations are generating major surveys of cell types and
connections in the mouse brain, collecting large amounts of data across modalities, spatial …

The mammalian cortex is a laminar structure containing many areas and cell types that are
densely interconnected in complex ways, and for which generalizable principles of …

INTRODUCTION In the absence of sensory inputs, the brain produces structured patterns of
activity, which can be as large as or larger than sensory-driven activity. Ongoing activity …