The field of heart valve biomechanics is a rapidly expanding, highly clinically relevant area
of research. While most valvular pathologies are rooted in biomechanical changes, the …

Objective The objective was to design and evaluate a clinically relevant, novel ex vivo
bicuspid aortic valve model that mimics the most common human phenotype with associated …

Objective Severe congenital aortic valve pathology in the growing patient remains a
challenging clinical scenario. Bicuspidization of the diseased aortic valve has proven to be a …

Objective The inclusion technique was developed to reinforce the pulmonary autograft to
prevent dilation after the Ross procedure. Anticommissural plication (ACP), a modification …

Background Several conduit configurations, such as straight graft (SG), Valsalva graft (VG),
anticommissural plication (ACP), and the Stanford modification (SMOD) technique, have …

Aortic regurgitation (AR) is one of the most prevalent cardiac valvular diseases, affecting up
to 13% of the population. 1 The pathophysiology of AR is dependent on the acuity of the …

Background Aortic regurgitation (AR) is one of the most common cardiac valvular diseases,
and it is frequently caused by cusp prolapse. However, the precise relationship of …

The Ross procedure using the inclusion technique with anticommissural plication (ACP) is
associated with excellent valve hemodynamics and favorable leaflet kinematics. The …

Purpose The valve-sparing aortic root replacement (VSARR) procedure was developed to
preserve the aortic valve apparatus to replace aneurysmal aortic roots with synthetic grafts …

Results: No animal died intraoperatively. One animal subjected to bicuspidalization died of
respiratory failure during postoperative imaging studies. Echocardiography showed the …